ArticleInternational journal of environmental research and public health2021
Gestational Diabetes Mellitus (GDM) Risk for Declared Family History of Diabetes, in Combination with BMI Categories.
Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Epidemiology of hyperglycemia during pregnancy in Ethiopia: prevalence, associated factors, and feto-maternal outcomes: systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- Correlation between TCF7L2 and CAPN10 gene polymorphisms and gestational diabetes mellitus in different geographical regions: a meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- The impact of prepregnancy BMI and family history of diabetes on the prevalence of gestational diabetes mellitus among Bulgarian women.BMC pregnancy and childbirth · 2026Observational
- The Placenta in Gestational Diabetes: An Integrated Review on Metabolic Pathways, Genetic, Epigenetic and Ultrasound Biomarkers for Clinical Perspectives.International journal of molecular sciences · 2026Review
- Development and validation of a model integrating clinical and metabolomic markers for gestational diabetes mellitus prediction.Frontiers in medicine · 2026Article
- ApoB and LDL partially explain the association between family history of diabetes and lower clinical pregnancy in women who conceived with PCOS.Frontiers in nutrition · 2026Article
- Comprehensive Review of Gestational Diabetes: Pathophysiology, Pharmacological Management and the Role of Pharmaceutical Care.Current drug safety · 2026Review
- Prevalence and determinants of first-trimester gestational diabetes mellitus among high-risk pregnant women attending primary health centres in Puducherry, India: a cross-sectional study.BMJ public health · 2026Article
- The correlation between serum magnesium, phosphorus, and calcium levels during pregnancy and the risk of gestational diabetes mellitus as well as adverse pregnancy outcomes.Frontiers in clinical diabetes and healthcare · 2026Article
- Analysis of related factors of spontaneous premature birth in pregnant women with gestational diabetes mellitus and construction of its nomogram risk prediction model.BMC pregnancy and childbirth · 2025Article
- Early Postpartum IL-10 and IL-37 Concentrations in Women with Gestational Diabetes Mellitus.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Risk factors for gestational diabetes mellitus and postpartum glucose intolerance: a retrospective study from a hospital specializing in infertility treatment.Scientific reports · 2025Article
- Investigating Pre-pregnancy and Late-Pregnancy E-cigarette Use Exposure and Gestational Diabetes Mellitus.Cureus · 2025Article
- Patient and contextual factors influence clinicians' decision making regarding universal screening for gestational diabetes: results of a factorial survey set in rural and remote Western Australia.BMC pregnancy and childbirth · 2025Article
- Assessment of Serum Uric Acid Levels Among Gestational Diabetes Patients in Erbil City.Cureus · 2025Article
- Genetic association of vitamin D receptor polymorphisms (ApaI, BsmI, and FokI) with gestational diabetes mellitus in North Indian women: a case-control study.Diabetology & metabolic syndrome · 2025Article
- PREGNANCY DISORDERS AND MATERNAL CONSEQUENCES: Maternal pre-pregnancy risks and postpartum consequences of gestational diabetes.Reproduction (Cambridge, England) · 2025Review
- Association of Historical Redlining With Gestational Diabetes Mellitus: The Mediating Role of BMI and Area Deprivation Index.Diabetes care · 2025Article
- Pregnancy log records and management of risk factors for gestational diabetes mellitus reduces its incidence.Frontiers in public health · 2025Article
- Osteopontin Levels in Maternal Serum, Cord Blood, and Breast Milk According to Gestational Diabetes Mellitus: A Case-Control Study.Nutrients · 2024Article
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1 author at 1 institution in 1 country.
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Abstract
Whether categories of family history of diabetes can act as independent risk factors for gestational diabetes mellitus (GDM-1, -2) has not yet been established, and neither has it been established how categories of body mass index (BMI) affect these relationships. A group of 912 women without chronic diseases, recruited in the first trimester, was investigated: 125 (13.7%) women developed GDM-1 (treated with diet); 21 (2.3%) women developed GDM-2 (treated with insulin); and a control group consisted of 766 non-diabetic women. A multiple logistic regression was used to evaluate adjusted odds ratios (AOR (95% confidence intervals)) of GDM-1 and GDM-2 for declared diabetes in the parents or grandparents (separately). These relationships were investigated in the whole cohort and subgroups of pre-pregnancy BMI. (1) Some categories of the family history were independent risk factors of GDM-1 or GDM-2. Compared to 'absence of diabetes in the family', women with diabetes in the father had a 3.68-fold increase in GDM-1 risk (AOR-b = 3.68 (2.23-6.07)), and women with diabetes in the mother had a 2.13-fold increase in GDM-1 risk (AOR-b = 2.13 (1.1-4.14)) and a 4.73-fold increase in GDM-2 risk (AOR-b = 4.73 (1.26-17.77)). Women with diabetes in the grandmother had a 2.34-fold increase in GDM-1 risk (AOR-b = 2.34 (1.29-4.24)). (2) The cumulative assessment of diabetes in the parents and/or grandparents was not related to the intensification of the risk of GDM, except for the increased risk of GDM-1 for diabetes in both mother and grandmothers simultaneously (AOR-b = 8.80 (1.16-66.57)), however, this group was very small. (3) The analyses in the subgroups of BMI categories showed that diabetes in the father was also an independent risk factor of GDM in the subgroup of pregnant women with normal BMI. In the subgroups of overweight and/or obesity, the risk of GDM for paternal and maternal diabetes was approximately twice as high as compared to the results of pregnant women with normal BMIs. Additionally, apart from the maternal influence of diabetes, the results suggest a significant influence of diabetes in the father on the risk of GDM, even (interestingly) in lean pregnant women.
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