Evidence map›Paper›PMID 34203505›Full record

ArticleAnimals : an open access journal from MDPI2021

Genome-Wide Association Study on Reproduction-Related Body-Shape Traits of Chinese Holstein Cows.

Xubin Lu, Ismail Mohamed Abdalla, Mudasir Nazar, Yongliang Fan, Zhipeng Zhang, Xinyue Wu, Tianle Xu, Zhangping Yang

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Unravelling the Genetic Mechanisms of Litter Traits in a Maternal Line of Pigs.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Single-Step Genome-Wide Association Study of Factors for Evaluated and Linearly Scored Traits in Swedish Warmblood Horses.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025
    Article
  7. Article
  8. Article
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  10. Review
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  12. Review
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  18. Article
  19. Molecular Marker-Assisted Selection ofAnimals : an open access journal from MDPI · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xubin LuCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225002, China.ORCID 0000-0001-6286-1517
Ismail Mohamed AbdallaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225002, China.
Mudasir NazarCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225002, China.
Yongliang FanCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225002, China.
Zhipeng ZhangCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225002, China.
Xinyue WuCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225002, China.
Tianle XuJoint International Research Laboratory of Agriculture and Agri-Product Safety, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0002-8479-3372
Zhangping YangCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225002, China.ORCID 0000-0002-5479-8447
Yangzhou University · CN

Funding

Earmarked Fund for Jiangsu Agricultural Industry Technology System JATS [2019]446National Natural Science Foundation of China 31872324Postgraduate Research & Practice Innovation Program of Yangzhou University XKYCX20_026
6 · The paper itself

Abstract

Reproduction is an important production activity for dairy cows, and their reproductive performance can directly affect the level of farmers' income. To better understand the genomic regions and biological pathways of reproduction-related traits of dairy cows, in the present study, three body shape traits-Loin Strength (LS), Rump Angle (RA), and Pin Width (PW)-were selected as indicators of the reproductive ability of cows, and we conducted genome-wide association analyses on them. The heritability of these three traits was medium, ranging from 0.20 to 0.38. A total of 11 significant single-nucleotide polymorphisms (SNPs) were detected associated with these three traits. Bioinformatics analysis was performed on genes close to the significant SNPs (within 200 Kb) of LS, RA, and PW, and we found that these genes were totally enriched in 20 gene ontology terms and six KEGG signaling pathways. Finally, the five genes

Indexed as

body-shape traitsChinese HolsteincowsGWASreproductionSNP

Identifiers

PMID34203505
PMCPMC8300307
OpenAlexW3175344947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.