Evidence map›Paper›PMID 34203435›Full record

ReviewCells2021

Man-Specific Lectins from Plants, Fungi, Algae and Cyanobacteria, as Potential Blockers for SARS-CoV, MERS-CoV and SARS-CoV-2 (COVID-19) Coronaviruses: Biomedical Perspectives.

Annick Barre, Els J M Van Damme, Mathias Simplicien, Sophie Le Poder, Bernard Klonjkowski, Hervé Benoist, David Peyrade, Pierre Rougé

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Article
  3. International journal of molecular sciences · 2024
    Review
  4. International journal of molecular sciences · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Genome-Wide Mining ofCurrent issues in molecular biology · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Lectins and lectibodies: potential promising antiviral agents.Cellular & molecular biology letters · 2022
    Review
  17. Plant lectins as prospective antiviral biomolecules in the search for COVID-19 eradication strategies.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Annick BarreUMR 152 PharmaDev, Institut de Recherche et Développement, Faculté de Pharmacie, Université Paul Sabatier, F-31062 Toulouse, France.ORCID 0000-0002-1360-8491
Els J M Van DammeDepartment of Biotechnology, Faculty of Bioscience Engineering, Ghent University, B-9000 Ghent, Belgium.ORCID 0000-0001-9848-766X
Mathias SimplicienUMR 152 PharmaDev, Institut de Recherche et Développement, Faculté de Pharmacie, Université Paul Sabatier, F-31062 Toulouse, France.ORCID 0000-0001-9303-5584
Sophie Le PoderUMR Virologie, INRA, ANSES, Ecole Nationale Vétérinaire d'Alfort, F-94700 Maisons-Alfort, France.
Bernard KlonjkowskiUMR Virologie, INRA, ANSES, Ecole Nationale Vétérinaire d'Alfort, F-94700 Maisons-Alfort, France.
Hervé BenoistUMR 152 PharmaDev, Institut de Recherche et Développement, Faculté de Pharmacie, Université Paul Sabatier, F-31062 Toulouse, France.
David PeyradeUMR5129 Laboratoire des Technologies de la Microélectonique, Université Grenoble Alpes, CNRS, CEA-Leti Minatec, CEDEX, F-38054 Grenoble, France.
Pierre RougéUMR 152 PharmaDev, Institut de Recherche et Développement, Faculté de Pharmacie, Université Paul Sabatier, F-31062 Toulouse, France.
Université Toulouse III - Paul Sabatier · FRÉcole Nationale Vétérinaire d'Alfort · FRGhent University · BEInstitut polytechnique de Grenoble · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Betacoronaviruses, responsible for the "Severe Acute Respiratory Syndrome" (SARS) and the "Middle East Respiratory Syndrome" (MERS), use the spikes protruding from the virion envelope to attach and subsequently infect the host cells. The coronavirus spike (S) proteins contain receptor binding domains (RBD), allowing the specific recognition of either the dipeptidyl peptidase CD23 (MERS-CoV) or the angiotensin-converting enzyme ACE2 (SARS-Cov, SARS-CoV-2) host cell receptors. The heavily glycosylated S protein includes both complex and high-mannose type

Indexed as

COVID-19COVID-19 Drug TreatmentCyanobacteriaDrug Delivery SystemsFungiHumansLectinsMiddle East Respiratory Syndrome CoronavirusPlantsProtein BindingSARS-CoV-2Severe acute respiratory syndrome-related coronavirusSpecies SpecificitySpike Glycoprotein, CoronavirusVirus InternalizationLectinsSpike Glycoprotein, Coronavirusalgae lectinsartocarpinbiomedical applicationscoronavirusesCOVID-19cyanobacteria lectinsfungi lectinsmannose-specific lectinsMERS-CoVpea lectinplant lectinsSARS-CoVSARS-CoV-2snowdrop lectin

Identifiers

PMID34203435
PMCPMC8305077
OpenAlexW3175702451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.