Evidence map›Paper›PMID 34203358›Full record

ArticleJournal of clinical medicine2021

Role of Concomitant Coronary Artery Bypass Grafting in Valve Surgery for Infective Endocarditis.

Mahmoud Diab, Thomas Lehmann, Carolyn Weber, Georgi Petrov, Maximilian Luehr, Payam Akhyari, Sems-Malte Tugtekin, P Christian Schulze, Marcus Franz, Martin Misfeld and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Mahmoud DiabDepartment of Cardiothoracic Surgery, Jena University Hospital-Friedrich Schiller University of Jena, 07747 Jena, Germany.
Thomas LehmannCenter of Clinical Studies, Jena University Hospital-Friedrich Schiller University of Jena, 07747 Jena, Germany.
Carolyn WeberDepartment of Cardiothoracic Surgery, Heart Center of the University of Cologne, 50937 Colonge, Germany.
Georgi PetrovDepartment of Cardiothoracic Surgery, Heinrich-Heine-University Duesseldorf, 40225 Duesseldof, Germany.
Maximilian LuehrDepartment of Cardiothoracic Surgery, Heart Center of the University of Cologne, 50937 Colonge, Germany.
Payam AkhyariDepartment of Cardiothoracic Surgery, Heinrich-Heine-University Duesseldorf, 40225 Duesseldof, Germany.ORCID 0000-0002-6452-8678
Sems-Malte TugtekinDepartment of Cardiac Surgery, Heart Center Dresden, 01307 Dresden, Germany.
P Christian SchulzeDepartment of Internal Medicine I, Jena University Hospital-Friedrich Schiller University of Jena, 07747 Jena, Germany.
Marcus FranzDepartment of Internal Medicine I, Jena University Hospital-Friedrich Schiller University of Jena, 07747 Jena, Germany.ORCID 0000-0001-6543-4684
Martin MisfeldDepartment of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney 2050, Australia.
Michael A BorgerDepartment of Cardiac Surgery, Heart Center Leipzig, 04289 Leipzig, Germany.
Klaus MatschkeDepartment of Cardiac Surgery, Heart Center Dresden, 01307 Dresden, Germany.
Thorsten WahlersDepartment of Cardiothoracic Surgery, Heart Center of the University of Cologne, 50937 Colonge, Germany.
Artur LichtenbergDepartment of Cardiothoracic Surgery, Heinrich-Heine-University Duesseldorf, 40225 Duesseldof, Germany.
Christian HaglDepartment of Cardiac Surgery, Ludwig Maximilian University Munich, 80539 Munich, Germany.
Torsten DoenstDepartment of Cardiothoracic Surgery, Jena University Hospital-Friedrich Schiller University of Jena, 07747 Jena, Germany.
Jena University Hospital · DEHeinrich Heine University Düsseldorf · DEUniversity of Cologne · DELeipzig Heart Institute · DELudwig-Maximilians-Universität München · DERoyal Prince Alfred Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is current practice to perform concomitant coronary artery bypass grafting (CABG) in patients with infective endocarditis (IE) who have relevant coronary artery disease (CAD). However, CABG may add complexity to the operation. We aimed to investigate the impact of concomitant CABG on perioperative outcomes in patients undergoing surgery for IE.

methodsWe retrospectively used data of surgically treated IE patients between 1994 and 2018 in six German cardiac surgery centers. We performed inverse probability weighting (IPW), multivariable adjustment, chi-square analysis, and Kaplan-Meier survival estimates.

resultsCAD was reported in 1242/4917 (25%) patients. Among them, 527 received concomitant CABG. After adjustment for basal characteristics between CABG and no-CABG patients using IPW, concomitant CABG was associated with higher postoperative stroke (26% vs. 21%,

conclusionIn endocarditis patients with CAD, adding CABG to valve surgery may be associated with a higher likelihood of postoperative stroke without adding long-term survival benefits. Therefore, in the absence of critical CAD, concomitant CABG may be omitted without impacting outcome. The results are limited due to a lack of data on the severity of CAD, and therefore there is a need for a randomized trial.

Indexed as

cardiac surgeryconcomitant coronary artery bypass graftingendocarditisstrokevalve

Identifiers

PMID34203358
PMCPMC8267636
OpenAlexW3177392218

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.