Evidence map›Paper›PMID 34203319›Full record

ArticleBiomedicines2021

Prognostic Significance of the Microbiome and Stromal Cells Phenotype in Esophagus Squamous Cell Carcinoma.

Olga Kovaleva, Polina Podlesnaya, Madina Rashidova, Daria Samoilova, Anatoly Petrenko, Valeria Mochalnikova, Vladimir Kataev, Yuri Khlopko, Andrey Plotnikov, Alexei Gratchev

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. IntratumoralScience advances · 2026
    Article
  3. Review
  4. Article
  5. Review
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  7. Article
  8. Review
  9. Article
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  12. Esophageal microflora in esophageal diseases.Frontiers in cellular and infection microbiology · 2023
    Review
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Olga KovalevaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Polina PodlesnayaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Madina RashidovaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Daria SamoilovaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Anatoly PetrenkoN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Valeria MochalnikovaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Vladimir KataevInstitute for Cellular and Intracellular Symbiosis, The Ural Branch of the Russian Academy of Sciences, 46000 Orenburg, Russia.ORCID 0000-0002-4411-8620
Yuri KhlopkoInstitute for Cellular and Intracellular Symbiosis, The Ural Branch of the Russian Academy of Sciences, 46000 Orenburg, Russia.ORCID 0000-0002-2880-3214
Andrey PlotnikovInstitute for Cellular and Intracellular Symbiosis, The Ural Branch of the Russian Academy of Sciences, 46000 Orenburg, Russia.ORCID 0000-0001-6830-4068
Alexei GratchevN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.ORCID 0000-0003-2137-1866
Institute of Cellular and Intracellular Symbiosis · RU

Funding

Russian Foundation for Basic Research 18-29-09069
6 · The paper itself

Abstract

Esophageal cancer is one of the most aggressive malignant neoplasms, with low survival rates and limited treatment options. In this study we analyzed the microbiome composition and the phenotype of inflammatory tumor infiltrate in squamous cell carcinoma of esophagus (ESCC) and examined possible relationships between them and their prognostic significance. We found that the predominant phyla of microorganisms found in both tumors and adjacent normal tissues were

Indexed as

canceresophagusmacrophagemicrobiomeprognosisstroma

Identifiers

PMID34203319
PMCPMC8301468
OpenAlexW3173557788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.