Evidence map›Paper›PMID 34203314›Full record

ArticleJournal of personalized medicine2021

Ultrasonography in the Differentiation of Endometriomas from Hemorrhagic Ovarian Cysts: The Role of Texture Analysis.

Roxana-Adelina Ștefan, Paul-Andrei Ștefan, Carmen Mihaela Mihu, Csaba Csutak, Carmen Stanca Melincovici, Carmen Bianca Crivii, Andrei Mihai Maluțan, Liviu Hîțu, Andrei Lebovici

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Application of artificial intelligence to ultrasound imaging for benign gynecological disorders: systematic review.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Roxana-Adelina ȘtefanHistology, Morphological Sciences Department, "Iuliu Hațieganu" University of Medicine and Pharmacy, Louis Pasteur Street, Number 4, 400349 Cluj-Napoca, Romania.
Paul-Andrei ȘtefanAnatomy and Embryology, Morphological Sciences Department, "Iuliu Hațieganu" University of Medicine and Pharmacy, Victor Babes, Street, Number 8, 400012 Cluj-Napoca, Romania.ORCID 0000-0001-5358-2137
Carmen Mihaela MihuHistology, Morphological Sciences Department, "Iuliu Hațieganu" University of Medicine and Pharmacy, Louis Pasteur Street, Number 4, 400349 Cluj-Napoca, Romania.
Csaba CsutakRadiology and Imaging Department, County Emergency Hospital, Cluj-Napoca, Clinicilor Street, Number 5, 400006 Cluj-Napoca, Romania.
Carmen Stanca MelincoviciHistology, Morphological Sciences Department, "Iuliu Hațieganu" University of Medicine and Pharmacy, Louis Pasteur Street, Number 4, 400349 Cluj-Napoca, Romania.
Carmen Bianca CriviiAnatomy and Embryology, Morphological Sciences Department, "Iuliu Hațieganu" University of Medicine and Pharmacy, Victor Babes, Street, Number 8, 400012 Cluj-Napoca, Romania.ORCID 0000-0001-5275-5753
Andrei Mihai MaluțanObstetrics and Gynecology Clinic "Dominic Stanca", County Emergency Hospital, 21 Decembrie 1989 Boulevard, Number 55, 400094 Cluj-Napoca, Romania.
Liviu HîțuDoctoral School, Iuliu Hațieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.ORCID 0000-0002-6040-3894
Andrei LeboviciRadiology and Imaging Department, County Emergency Hospital, Cluj-Napoca, Clinicilor Street, Number 5, 400006 Cluj-Napoca, Romania.ORCID 0000-0002-2815-2132
Iuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

European Social Fund 380/6/13/125171
6 · The paper itself

Abstract

The ultrasonographic (US) features of endometriomas and hemorrhagic ovarian cysts (HOCs) are often overlapping. With the emergence of new computer-aided diagnosis techniques, this is the first study to investigate whether texture analysis (TA) could improve the discrimination between the two lesions in comparison with classic US evaluation. Fifty-six ovarian cysts (endometriomas, 30; HOCs, 26) were retrospectively included. Four classic US features of endometriomas (low-level internal echoes, perceptible walls, no solid components, and less than five locules) and 275 texture parameters were assessed for every lesion, and the ability to identify endometriomas was evaluated through univariate, multivariate, and receiver operating characteristics analyses. The sensitivity (Se) and specificity (Sp) were calculated with 95% confidence intervals (CIs). The texture model, consisting of seven independent predictors (five variations of difference of variance, image contrast, and the 10th percentile; 100% Se and 100% Sp), was able to outperform the ultrasound model composed of three independent features (low-level internal echoes, perceptible walls, and less than five locules; 74.19% Se and 84.62% Sp) in the diagnosis of endometriomas. The TA showed statistically significant differences between the groups and high diagnostic value, but it remains unclear if the textures reflect the intrinsic histological characteristics of the two lesions.

Indexed as

computer-aided diagnosisendometriomahemorrhagic cysttexture analysisultrasonography

Identifiers

PMID34203314
PMCPMC8306221
OpenAlexW3177374708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.