Evidence map›Paper›PMID 34203260›Full record

ReviewMetabolites2021

Altered Ca

Antonio Michelucci, Chen Liang, Feliciano Protasi, Robert T Dirksen

Open access · goldAbstract readReview
In one paragraph

Review in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 62 citations in OpenAlex.

  1. Nitric-Oxide-Inducing Factors on Vitamin D Changes in Older People Susceptible to Suffer from Sarcopenia.International journal of environmental research and public health · 2022
    Trial
  2. Article
  3. The two faces of mitochondrial CaJournal of physiology and biochemistry · 2026
    Review
  4. Review
  5. Article
  6. Review
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  19. Review
  20. Effects of aging on calcium channels in skeletal muscle.Frontiers in molecular biosciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Antonio MichelucciDNICS, Department of Neuroscience, Imaging, and Clinical Sciences, University G. d'Annunzio of Chieti-Pescara, I-66100 Chieti, Italy.
Chen LiangDepartment of Pharmacology and Physiology, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0002-5562-350X
Feliciano ProtasiCAST, Center for Advanced Studies and Technology, DMSI, Department of Medicine and Aging Sciences, University G. d'Annunzio of Chieti-Pescara, I-66100 Chieti, Italy.ORCID 0000-0002-0213-7591
Robert T DirksenDepartment of Pharmacology and Physiology, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY 14642, USA.
University of Chieti-Pescara · ITUniversity of Rochester Medical Center · US

Funding

Molecular Mechanism and Functional Role of SOCE in Skeletal MuscleR01AR059646 · NIAMS · UNIVERSITY OF ROCHESTER · PI DIRKSEN, ROBERT T · 2010 to 2020
$3.6M
Fondazione Telethon GGP19231NIAMS NIH HHS R01 AR059646NIH HHS AR059646
6 · The paper itself

Abstract

Skeletal muscle contraction relies on both high-fidelity calcium (Ca

Indexed as

atrophyCa2+ signalingmitochondriaoxidative stresssarcopeniaskeletal muscle disease

Identifiers

PMID34203260
PMCPMC8304741
OpenAlexW3175470195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.