Evidence map›Paper›PMID 34203247›Full record

ReviewInternational journal of molecular sciences2021

The V-ATPase

Anh Chu, Ralph A Zirngibl, Morris F Manolson

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Identifying rare variants in genes related to bone phenotypes in a cohort of postmenopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  8. Review
  9. V-ATPase in cancer: mechanistic insights and therapeutic potentials.Cell communication and signaling : CCS · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Lysosomal biogenesis and function in osteoclasts: a comprehensive review.Frontiers in cell and developmental biology · 2024
    Review
  14. Article
  15. Article
  16. Structural and Functional Diversity of Two ATP-Driven Plant Proton Pumps.International journal of molecular sciences · 2023
    Review
  17. Review
  18. Article
  19. The V-ATPases in cancer and cell death.Cancer gene therapy · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anh ChuFaculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
Ralph A ZirngiblFaculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
Morris F ManolsonFaculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
University of Toronto · CA

Funding

CIHR PJT-148508
6 · The paper itself

Abstract

This review focuses on one of the 16 proteins composing the V-ATPase complex responsible for resorbing bone: the

Indexed as

AnimalsBone ResorptionHumansMutationOsteoclastsOsteopetrosisVacuolar Proton-Translocating ATPasesVacuolar Proton-Translocating ATPasesanti-resorptive therapeuticsATP6V0A3ATP6V1CboneOC-116 kDaosteoclastsosteopetrosisosteoporosissignalosomeTCIRG1V-ATPaseV-type proton ATPase 116 kDa subunit a3

Identifiers

PMID34203247
PMCPMC8269383
OpenAlexW3174339275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.