Evidence map›Paper›PMID 34203217›Full record

ArticleBiology2021

Discovery of Novel GMPS Inhibitors of

Jing Nan, Shaoran Zhang, Ping Zhan, Ling Jiang

Open access · goldAbstract read
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Construction of RecombinantMicroorganisms · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jing NanMinistry of Education Key Laboratory of Plant Biology, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0002-2635-5219
Shaoran ZhangState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.
Ping ZhanMinistry of Education Key Laboratory of Plant Biology, Huazhong Agricultural University, Wuhan 430070, China.
Ling JiangMinistry of Education Key Laboratory of Plant Biology, Huazhong Agricultural University, Wuhan 430070, China.
Huazhong Agricultural University · CN

Funding

National key research and development plan 2018YFD0201505National key research and development plan 2019YFD1001802National Natural Science Foundation of China No. 31872064
6 · The paper itself

Abstract

Citrus production is facing an unprecedented problem because of huanglongbing (HLB) disease. Presently, no effective HLB-easing method is available when citrus becomes infected. Guanosine 5'-monophosphate synthetase (GMPS) is a key protein in the de novo synthesis of guanine nucleotides. GMPS is used as an attractive target for developing agents that are effective against the patogen infection. In this research, homology modeling, structure-based virtual screening, and molecular docking were used to discover the new inhibitors against

Indexed as

Candidatus Liberibacter asiaticusenzyme activityguanosine 5′-monophosphate synthetasemolecular dockingvirtual screening

Identifiers

PMID34203217
PMCPMC8301025
OpenAlexW3173677133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.