Evidence map›Paper›PMID 34203211›Full record

ArticleInternational journal of molecular sciences2021

Prognostic and Therapeutic Implications of Immune Classification by CD8

Rocío García-Marín, Sara Reda, Cristina Riobello, Virginia N Cabal, Laura Suárez-Fernández, Blanca Vivanco, César Álvarez-Marcos, Fernando López, José L Llorente, Mario A Hermsen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Clinical, genetic and immunohistochemical characterization of sinonasal tumors with neuroectodermal differentiation.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. CD8JCO precision oncology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Rocío García-MarínDepartment Head and Neck Oncology, Instituto de Investigación Sanitaria del Principado de Asturias, 33011 Oviedo, Spain.ORCID 0000-0003-0331-2002
Sara RedaDepartment Otolaryngology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.ORCID 0000-0002-9150-3249
Cristina RiobelloDepartment Head and Neck Oncology, Instituto de Investigación Sanitaria del Principado de Asturias, 33011 Oviedo, Spain.
Virginia N CabalDepartment Head and Neck Oncology, Instituto de Investigación Sanitaria del Principado de Asturias, 33011 Oviedo, Spain.
Laura Suárez-FernándezDepartment Head and Neck Oncology, Instituto de Investigación Sanitaria del Principado de Asturias, 33011 Oviedo, Spain.
Blanca VivancoDepartment Pathology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
César Álvarez-MarcosDepartment Otolaryngology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Fernando LópezDepartment Otolaryngology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.ORCID 0000-0001-7019-9746
José L LlorenteDepartment Otolaryngology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Mario A HermsenDepartment Head and Neck Oncology, Instituto de Investigación Sanitaria del Principado de Asturias, 33011 Oviedo, Spain.
Hospital Universitario Central de Asturias · ESInstituto de Investigación Sanitaria del Principado de Asturias · ES

Funding

Ayudas a Grupos PCTI Principado de Asturias IDI2018/155Centro de Investigación Biomédica en Red de Cancer CB16/12/00390Fundación AECC CICPF16008HERM
6 · The paper itself

Abstract

Sinonasal squamous cell carcinoma (SNSCC) is an aggressive tumor predominantly arising in the maxillary sinus and nasal cavities. Advances in imaging, surgical and radiotherapeutic techniques have reduced complications and morbidity; however, the prognosis generally remains poor, with an overall 5-year survival rate of 30-50%. As immunotherapy may be a new therapeutic option, we analyzed CD8

Indexed as

B7-H1 AntigenCarcinoma, Squamous CellCD8-Positive T-LymphocytesFemaleHumansImmunotherapyKaplan-Meier EstimateLymphocytes, Tumor-InfiltratingMalePrognosisB7-H1 AntigenCD8+ TILsimmunotherapyPD-L1sinonasal cancersquamous cell carcinoma

Identifiers

PMID34203211
PMCPMC8268278
OpenAlexW3175965727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.