Evidence map›Paper›PMID 34203184›Full record

ArticleCancers2021

The Impact of Extracellular Ca

Julita Kulbacka, Nina Rembiałkowska, Anna Szewczyk, Helena Moreira, Anna Szyjka, Irutė Girkontaitė, Kamil P Grela, Vitalij Novickij

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Julita KulbackaDepartment of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0001-8272-5440
Nina RembiałkowskaDepartment of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0001-9435-9409
Anna SzewczykDepartment of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Helena MoreiraDepartment of Basic Medical Science, Faculty of Pharmacy, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0002-8084-3686
Anna SzyjkaDepartment of Basic Medical Science, Faculty of Pharmacy, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Irutė GirkontaitėDepartment of Immunology, State Research Institute Centre for Innovative Medicine, 08406 Vilnius, Lithuania.ORCID 0000-0002-3659-3202
Kamil P GrelaDepartment of Drugs Form Technology, Faculty of Pharmacy, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Vitalij NovickijInstitute of High Magnetic Fields, Vilnius Gediminas Technical University, 10223 Vilnius, Lithuania.
Wroclaw Medical University · PLState Research Institute Centre for Innovative Medicine · LTUniversity of Wrocław · PLVilnius Gediminas Technical University · LT

Funding

Lietuvos Mokslo Taryba No.: S-MIP-19-22 (PI: V. Novickij)Narodowym Centrum Nauki SONATA BIS 6 (2016/22/E/NZ5/00671; PI: J. Kulbacka)
6 · The paper itself

Abstract

(1) Background: Calcium electroporation (CaEP) is based on the application of electrical pulses to permeabilize cells (electroporation) and allow cytotoxic doses of calcium to enter the cell. (2) Methods: In this work, we have used doxorubicin-resistant (DX) and non-resistant models of human breast cancer (MCF-7/DX, MCF-7/WT) and colon cancer cells (LoVo, LoVo/DX), and investigated the susceptibility of the cells to extracellular Ca

Indexed as

calcium ionselectroporation drug resistancehuman adenocarcinomamembrane permeabilization

Identifiers

PMID34203184
PMCPMC8268418
OpenAlexW3173955916

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.