Molecular Basis for the Activation of Human Innate Immune Response by the Flagellin Derived from Plant-Pathogenic Bacterium,

Nasir Javaid, Hiroyuki Hirai, Fang-Sik Che, Sangdun Choi

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

0.2field-weighted citation impact, top 50% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

Role of EDA Fibronectin and Toll-like Receptor 5 in the Development of the Tumor Microenvironment in Triple Negative Breast Cancer.Cancers · 2026
Article
Identification and Preliminary mRNA Validation of Key Genes Associated with Tolerogenic Dendritic Cells in Keloid Based on Transcriptome Data.Clinical, cosmetic and investigational dermatology · 2026
Article
Metagenomic analysis of microbiome spatial dynamics in urban river confluence affected by city wastewater.Genomics & informatics · 2025
Article
NLRC4 methylation and its response to intravenous immunoglobulin therapy in Kawasaki disease: a case control study.BMC pediatrics · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Nasir JavaidDepartment of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.

Hiroyuki HiraiGraduate School of Bio-Science, Nagahama Institute of Bio-Science and Technology, 1266, Tamura Nagahama, Shiga 526-0829, Japan.

Fang-Sik CheGraduate School of Bio-Science, Nagahama Institute of Bio-Science and Technology, 1266, Tamura Nagahama, Shiga 526-0829, Japan.

Sangdun ChoiDepartment of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.ORCID 0000-0001-5920-7848

Ajou University · KRNagahama Institute of Bio-Science and Technology · JP

Funding

National Research Foundation of Korea NRF- 2020R1F1A1071517, 2019M3D1A1078940, and 2019R1A6A1A11051471

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Calcium-Binding ProteinsCARD Signaling Adaptor ProteinsComamonadaceaeFibroblastsFlagellinHumansImmunity, InnateInterleukin-18Interleukin-6MacrophagesSignal TransductionTumor Necrosis Factor-alphaCalcium-Binding ProteinsCARD Signaling Adaptor ProteinsFlagellinInterleukin-18Interleukin-6NLRC4 protein, humanTumor Necrosis Factor-alphaAcidovorax avenaeflagellinNLRC4TLR5

Identifiers

PMID34203170

DOI10.3390/ijms22136920

PMCPMC8268093

OpenAlexW3175070458

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.