Evidence map›Paper›PMID 34202952›Full record

ArticleViruses2021

The Clinical Presentation of Puumala Hantavirus Induced Hemorrhagic Fever with Renal Syndrome Is Related to Plasma Glucose Concentration.

Johanna Tietäväinen, Satu Mäkelä, Heini Huhtala, Ilkka H Pörsti, Tomas Strandin, Antti Vaheri, Jukka Mustonen

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Johanna TietäväinenFaculty of Medicine and Health Technology, Tampere University, 33520 Tampere, Finland.ORCID 0000-0003-1882-0691
Satu MäkeläFaculty of Medicine and Health Technology, Tampere University, 33520 Tampere, Finland.ORCID 0000-0001-6967-2401
Heini HuhtalaFaculty of Social Sciences, Tampere University, 33520 Tampere, Finland.ORCID 0000-0003-1372-430X
Ilkka H PörstiFaculty of Medicine and Health Technology, Tampere University, 33520 Tampere, Finland.ORCID 0000-0002-4905-7564
Tomas StrandinDepartment of Virology, Medicum, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0002-2454-7479
Antti VaheriDepartment of Virology, Medicum, University of Helsinki, 00290 Helsinki, Finland.
Jukka MustonenFaculty of Medicine and Health Technology, Tampere University, 33520 Tampere, Finland.
Tampere University · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Puumala hantavirus (PUUV) causes a hemorrhagic fever with renal syndrome characterized by thrombocytopenia, increased capillary leakage, and acute kidney injury (AKI). As glucosuria at hospital admission predicts the severity of PUUV infection, we explored how plasma glucose concentration associates with disease severity. Plasma glucose values were measured during hospital care in 185 patients with PUUV infection. They were divided into two groups according to maximum plasma glucose concentration: P-Gluc < 7.8 mmol/L (

Indexed as

AdolescentAdultAgedBlood GlucoseCohort StudiesFemaleHemorrhagic Fever with Renal SyndromeHospitalizationHumansHyperglycemiaKidneyKidney Function TestsMaleMiddle AgedPuumala virusSeverity of Illness IndexBlood GlucoseAKIcapillary leakageendothelial damagehyperglycemiapuumala hantavirusthrombocytopenia

Identifiers

PMID34202952
PMCPMC8235586
OpenAlexW3174834930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.