Evidence map›Paper›PMID 34202951›Full record

ArticleMolecules (Basel, Switzerland)2021

Efficient One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1

Giovanna Bosica, Fiona Cachia, Riccardo De Nittis, Nicole Mariotti

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Design, Synthesis,ACS omega · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giovanna BosicaDepartment of Chemistry, University of Malta, 2080 Msida, Malta.ORCID 0000-0002-5674-870X
Fiona CachiaDepartment of Chemistry, University of Malta, 2080 Msida, Malta.
Riccardo De NittisDepartment of Chemistry, University of Malta, 2080 Msida, Malta.
Nicole MariottiDepartment of Chemistry, University of Malta, 2080 Msida, Malta.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multicomponent reactions are considered to be of increasing importance as time progresses due to the economic and environmental advantages such strategies entail. The three-component Biginelli reaction involves the combination of an aldehyde, a β-ketoester and urea to produce 3,4-dihydropyrimidin-2(1

Indexed as

Biginelli reactionheterogeneous catalysismulticomponent reactionone-potsolvent-freesupported heteropoly acid

Identifiers

PMID34202951
PMCPMC8235482

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.