ReviewJournal of clinical medicine2021
Outcomes of Universal Newborn Screening Programs: Systematic Review.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 5 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Quality measures of two-stage newborn hearing screening: systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Early Hearing Detection and Intervention programmes for neonates, infants and children in non-Asian low-income and middle-income countries: a systematic review.BMJ paediatrics open · 2024Pooled it
- Clinical practice guideline: Interventions for Developmental Language Delay and Disorders.Deutsches Arzteblatt international · 2024Guideline
- Early hearing detection and intervention (EHDI) programmes for infants and young children in low-income and middle-income countries in Asia: a systematic review.BMJ paediatrics open · 2023Pooled it
- Effectiveness of universal newborn hearing screening: A systematic review and meta-analysis.Journal of global health · 2022Pooled it
- Sensorineural hearing loss in early childhood after passing newborn hearing screening.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Practice and challenges of newborn hearing screening: analysis of a five-year database in Italy.Italian journal of pediatrics · 2026Article
- From clusters to clinical rules: unsupervised machine learning identifies four newborn hearing phenotypes with bedside risk stratification.BMC pediatrics · 2026Article
- Clinical Diagnostics After Failed Hearing Screening in People With Intellectual Disabilities Do Not Often Take Place.Journal of intellectual disability research : JIDR · 2026Article
- Machine learning-enhanced behavioural approach to detecting reactions to sound in infants and toddlers: proof-of-concept study.International journal of audiology · 2026Article
- Article
- Data-Related and Methodological Challenges in Assessing the Cost-Effectiveness of Traditional and Genomic Newborn Screening Programs.Applied health economics and health policy · 2026Review
- The impact of a two-stage newborn hearing screening protocol for early diagnosis of hearing loss.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026Article
- A survey of strategies for the early diagnosis of hearing loss in infants: a scoping review.CoDAS · 2026Article
- Article
- Article
- Auditory Perception Outcomes in Children with Deafness and Additional Disabilities 12 Months After Cochlear Implant Activation.Audiology research · 2025Article
- Parental Evaluation of a Responsive Parenting Program for Infants with Hearing Loss.Children (Basel, Switzerland) · 2025Article
- Development and Beta Validation of an mHealth-Based Hearing Screener (SRESHT) for Young Children in Resource-Limited Countries: Pilot Validation Study.JMIR formative research · 2025Article
- Parental/Caregiver Satisfaction and Anxiety with Newborn Hearing Screening Program in Dakshina Karnataka, India - A Questionnaire Based Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThis systematic review examined the outcomes (age of identification and intervention, developmental outcomes, cost-effectiveness, and adverse effects on parents) of universal newborn hearing screening (UNHS) for children with permanent congenital hearing loss (PCHL). MATERIALS AND
methodsMultiple electronic databases were interrogated in March and April 2020 with further reports identified from article citations and unpublished literature. UNHS reports in English with comparisons of outcomes of infants who were not screened, and infants identified through other hearing screening programs.
results30 eligible reports from 14 populations with 7,325,138 infants screened through UNHS from 1616 non-duplicate references were included. UNHS results in a lower age of identification, amplification, and the initiation of early intervention services and better language/literacy development. Better speech perception/production were shown in younger, but not in older, children with early identification after UNHS. No significant findings were found for behavior problems and quality of life. UNHS was found to be cost-effective in terms of savings to society. In addition, no significant parental harm was noted as a result of UNHS.
conclusionsIn highly developed countries, significantly better outcomes were found for children identified early through UNHS programs. Early language development predicts later literacy and language development.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.