Evidence map›Paper›PMID 34202806›Full record

ArticleAnimals : an open access journal from MDPI2021

Silver and Copper Nanoparticles Inhibit Biofilm Formation by Mastitis Pathogens.

Agata Lange, Agnieszka Grzenia, Mateusz Wierzbicki, Barbara Strojny-Cieslak, Aleksandra Kalińska, Marcin Gołębiewski, Daniel Radzikowski, Ewa Sawosz, Sławomir Jaworski

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 59 citations in OpenAlex.

  1. FeBiofilm · 2026
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  20. Green Extracellular Synthesis of Silver Nanoparticles byMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Agata LangeDepartment of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.ORCID 0000-0003-1523-083X
Agnieszka GrzeniaDepartment of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.
Mateusz WierzbickiDepartment of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.ORCID 0000-0003-3623-8929
Barbara Strojny-CieslakDepartment of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.ORCID 0000-0002-2642-5491
Aleksandra KalińskaDepartment of Animal Breeding, Institute of Animal Sciences, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.ORCID 0000-0001-5861-0635
Marcin GołębiewskiDepartment of Animal Breeding, Institute of Animal Sciences, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.
Daniel RadzikowskiDepartment of Animal Breeding, Institute of Animal Sciences, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.ORCID 0000-0001-9143-8339
Ewa SawoszDepartment of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.
Sławomir JaworskiDepartment of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.ORCID 0000-0002-4619-941X
Warsaw University of Life Sciences · PL

Funding

National Center for Research and Development LID-ER/6/0070/L-7/15/NCBR/2016
6 · The paper itself

Abstract

Bovine mastitis is a common bovine disease, frequently affecting whole herds of cattle. It is often caused by resistant microbes that can create a biofilm structure. The rapidly developing scientific discipline known as nanobiotechnology may help treat this illness, thanks to the extraordinary properties of nanoparticles. The aim of the study was to investigate the inhibition of biofilms created by mastitis pathogens after treatment with silver and copper nanoparticles, both individually and in combination. We defined the physicochemical properties and minimal inhibitory concentration of the nanoparticles and observed their interaction with the cell membrane, as well as the extent of biofilm reduction. The results show that the silver-copper complex was the most active of all nanomaterials tested (biofilm was reduced by nearly 100% at a concentration of 200 ppm for each microorganism species tested). However, silver nanoparticles were also effective individually (biofilm was also reduced by nearly 100% at a concentration of 200 ppm, but at concentrations of 50 and 100 ppm, the extent of reduction was lower than for the complex). Nanoparticles can be used in new alternative therapies to treat bovine mastitis.

Indexed as

biofilmbovine mastitiscopper nanoparticlesmastitis pathogenssilver-copper complexsilver nanoparticles

Identifiers

PMID34202806
PMCPMC8300152
OpenAlexW3174613630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.