Evidence map›Paper›PMID 34202712›Full record

ReviewInternational journal of molecular sciences2021

Bioaccessibility and Bioavailability of Minerals in Relation to a Healthy Gut Microbiome.

Viktor Bielik, Martin Kolisek

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 3 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 3 syntheses or guidelines pooled it, 154 citations in OpenAlex.

  1. Pooled it
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  16. Synergistic Effects of 25-Hydroxyvitamin DAnimals : an open access journal from MDPI · 2026
    Article
  17. Assessment of Zinc Content in Food Supplements.Foods (Basel, Switzerland) · 2026
    Article
  18. Synergistic effects ofFrontiers in nutrition · 2026
    Article
  19. The Aging Gut-Brain Axis: Effects of Dietary Polyphenols and Metal Exposure.Chronic diseases and translational medicine · 2025
    Review
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Viktor BielikDepartment of Biological and Medical Science, Faculty of Physical Education and Sport, Comenius University in Bratislava, 81469 Bratislava, Slovakia.ORCID 0000-0001-9525-4983
Martin KolisekBiomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 03601 Martin, Slovakia.
Comenius University Bratislava · SK

Funding

The Ministry of Education, Science, Research and Sport of the Slovak Republic VEGA 1/0260/21The Slovak Research and Development Agency APVV-17-0099
6 · The paper itself

Abstract

Adequate amounts of a wide range of micronutrients are needed by body tissues to maintain health. Dietary intake must be sufficient to meet these micronutrient requirements. Mineral deficiency does not seem to be the result of a physically active life or of athletic training but is more likely to arise from disturbances in the quality and quantity of ingested food. The lack of some minerals in the body appears to be symbolic of the modern era reflecting either the excessive intake of empty calories or a negative energy balance from drastic weight-loss diets. Several animal studies provide convincing evidence for an association between dietary micronutrient availability and microbial composition in the gut. However, the influence of human gut microbiota on the bioaccessibility and bioavailability of trace elements in human food has rarely been studied. Bacteria play a role by effecting mineral bioavailability and bioaccessibility, which are further increased through the fermentation of cereals and the soaking and germination of crops. Moreover, probiotics have a positive effect on iron, calcium, selenium, and zinc in relation to gut microbiome composition and metabolism. The current literature reveals the beneficial effects of bacteria on mineral bioaccessibility and bioavailability in supporting both the human gut microbiome and overall health. This review focuses on interactions between the gut microbiota and several minerals in sport nutrition, as related to a physically active lifestyle.

Indexed as

DietGastrointestinal MicrobiomeAnimalsBiological AvailabilityCalcium, DietaryGastrointestinal AbsorptionHumansMicronutrientsMineralsProbioticsTrace ElementsCalcium, DietaryMicronutrientsMineralsTrace ElementsFe deficiencygut microbiotamagnesiummicronutrientphysical fitnesstrace element

Identifiers

PMID34202712
PMCPMC8268569
OpenAlexW3176307767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.