Evidence map›Paper›PMID 34202630›Full record

ArticleMolecules (Basel, Switzerland)2021

Environment-Sensitive Fluorescence of 7-Nitrobenz-2-oxa-1,3-diazol-4-yl (NBD)-Labeled Ligands for Serotonin Receptors.

Parijat Sarkar, Kaleeckal G Harikumar, Satinder S Rawat, Sanjib Das, Tushar K Chakraborty, Amitabha Chattopadhyay

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Parijat SarkarCSIR-Centre for Cellular & Molecular Biology, Uppal Road, Hyderabad 500 007, India.ORCID 0000-0001-9435-5600
Kaleeckal G HarikumarCSIR-Centre for Cellular & Molecular Biology, Uppal Road, Hyderabad 500 007, India.
Satinder S RawatCSIR-Centre for Cellular & Molecular Biology, Uppal Road, Hyderabad 500 007, India.
Sanjib DasCSIR-Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500 007, India.ORCID 0000-0002-0092-7493
Tushar K ChakrabortyCSIR-Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500 007, India.
Amitabha ChattopadhyayCSIR-Centre for Cellular & Molecular Biology, Uppal Road, Hyderabad 500 007, India.ORCID 0000-0002-2618-2565
Centre for Cellular and Molecular Biology · INIndian Institute of Chemical Technology · IN

Funding

CSIR-Centre for Cellular and Molecular Biology Core Support
6 · The paper itself

Abstract

Serotonin is a neurotransmitter that plays a crucial role in the regulation of several behavioral and cognitive functions by binding to a number of different serotonin receptors present on the cell surface. We report here the synthesis and characterization of several novel fluorescent analogs of serotonin in which the fluorescent NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) group is covalently attached to serotonin. The fluorescent ligands compete with the serotonin

Indexed as

AnimalsAzolesCell MembraneCHO CellsCricetulusFluorescent DyesHumansLigandsNitrobenzenesReceptor, Serotonin, 5-HT1A7-nitrobenz-2-oxa-1,3-diazol-4-ylAzolesFluorescent DyesLigandsNitrobenzenesReceptor, Serotonin, 5-HT1Aconfocal microscopyNBDREESserotoninserotonin1A receptorspectral imaging

Identifiers

PMID34202630
PMCPMC8270269
OpenAlexW3177169786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.