Evidence map›Paper›PMID 34202548›Full record

ArticleMolecules (Basel, Switzerland)2021

A Bioactive Compound from

Weijia Zhang, Chang Peng, Xue Shen, Yuemei Yuan, Wei Zhang, Chunjuan Yang, Meicun Yao

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Therapeutic Potential of Ziyuglycosides fromDrug design, development and therapy · 2026
    Review
  2. Article
  3. Review
  4. The processedFrontiers in immunology · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Wound-Healing Potential of Rhoifolin-Rich Fraction Isolated fromPharmaceuticals (Basel, Switzerland) · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Weijia ZhangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Chang PengSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.
Xue ShenSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Yuemei YuanSchool of Ecology, Sun Yat-sen University, 6# Ming De Yuan, Guangzhou University City, Guangzhou 510006, China.
Wei ZhangState Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Taipa, Macau, China.
Chunjuan YangDepartment of Pharmaceutical Analysis and Analytical Chemistry, College of Pharmacy Harbin Medical University, Harbin 150081, China.
Meicun YaoSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.ORCID 0000-0002-4372-6528
Sun Yat-sen University · CNMacau University of Science and Technology · MOHarbin Medical University · CN

Funding

National Natural Science Foundation of China 81973552; 81573551
6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the most common cancer in the world. The first line chemotherapeutic agent, 5-fluorouracil (5-FU), plays a predominant role in the clinical treatment of CRC. However, with the wide use of 5-FU, more and more CRC patients have been obtaining drug resistance to 5-FU, which leads to a large amount of treatment failures. One of the effective strategies to overcome this obstacle is to find bioactive natural products from traditional medicine. In our previous work,

Indexed as

PhytochemicalsCell DeathCell Line, TumorCell ProliferationColorectal NeoplasmsDrug Resistance, NeoplasmFluorouracilHumansSanguisorbaFluorouracilPhytochemicalsAGEapoptosisautophagycolorectal cancerWnt/β-catenin signaling pathway

Identifiers

PMID34202548
PMCPMC8270258
OpenAlexW3175358686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.