Evidence map›Paper›PMID 34202483›Full record

ReviewSensors (Basel, Switzerland)2021

Paper-Based Immunosensors with Bio-Chemiluminescence Detection.

Maria Maddalena Calabretta, Martina Zangheri, Donato Calabria, Antonia Lopreside, Laura Montali, Elisa Marchegiani, Ilaria Trozzi, Massimo Guardigli, Mara Mirasoli, Elisa Michelini

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  14. Fundamentals of Biosensors and Detection Methods.Advances in experimental medicine and biology · 2022
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria Maddalena CalabrettaDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-5673-3073
Martina ZangheriDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.
Donato CalabriaDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-8215-9458
Antonia LopresideDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.
Laura MontaliDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.
Elisa MarchegianiDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.
Ilaria TrozziDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.
Massimo GuardigliDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.
Mara MirasoliDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.
Elisa MicheliniDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-8651-0575

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca 2017Y2PAB8Ministero dell'Istruzione, dell'Università e della Ricerca 2017YER72KPartnership for Research and Innovation in the Mediterranean Area Fedkito
6 · The paper itself

Abstract

Since the introduction of paper-based analytical devices as potential diagnostic platforms a few decades ago, huge efforts have been made in this field to develop systems suitable for meeting the requirements for the point-of-care (POC) approach. Considerable progress has been achieved in the adaptation of existing analysis methods to a paper-based format, especially considering the chemiluminescent (CL)-immunoassays-based techniques. The implementation of biospecific assays with CL detection and paper-based technology represents an ideal solution for the development of portable analytical devices for on-site applications, since the peculiarities of these features create a unique combination for fitting the POC purposes. Despite this, the scientific production is not paralleled by the diffusion of such devices into everyday life. This review aims to highlight the open issues that are responsible for this discrepancy and to find the aspects that require a focused and targeted research to make these methods really applicable in routine analysis.

Indexed as

Biosensing TechniquesLuminescenceImmunoassayPoint-of-Care Systemsbio-chemiluminescencebiosensorimmunosensorpaper-basedpoint-of-care

Identifiers

PMID34202483
PMCPMC8271422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.