Evidence map›Paper›PMID 34202425›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Perioperative GABA Blood Concentrations in Infants with Cyanotic and Non-Cyanotic Congenital Heart Diseases.

Angela Satriano, Alessandro Varrica, Alessandro Frigiola, Alessandro Graziosi, Caterina Di Battista, Adele Patrizia Primavera, Giacomo Centini, Antonio Maconi, Chiara Strozzi, Antonio D W Gavilanes and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Identification ofDiagnostics (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Angela SatrianoDepartment of Pediatric Cardiac Surgery IRCCS San Donato Milanese Hospital, 20097 San Donato Milanese, Italy.
Alessandro VarricaDepartment of Pediatric Cardiac Surgery IRCCS San Donato Milanese Hospital, 20097 San Donato Milanese, Italy.
Alessandro FrigiolaDepartment of Pediatric Cardiac Surgery IRCCS San Donato Milanese Hospital, 20097 San Donato Milanese, Italy.
Alessandro GraziosiNeonatal Intensive Care Unit, Department of Pediatrics, University of Chieti, 65100 Chieti, Italy.
Caterina Di BattistaNeonatal Intensive Care Unit, Department of Pediatrics, University of Chieti, 65100 Chieti, Italy.ORCID 0000-0001-5454-3949
Adele Patrizia PrimaveraNeonatal Intensive Care Unit, Department of Pediatrics, University of Chieti, 65100 Chieti, Italy.
Giacomo CentiniDepartment of Maternal Fetal and Neonatal Medicine, C. Arrigo Children's Hospital Alessandria, 15100 Alessandria, Italy.
Antonio MaconiDepartment of Maternal Fetal and Neonatal Medicine, C. Arrigo Children's Hospital Alessandria, 15100 Alessandria, Italy.
Chiara StrozziDepartment of Maternal Fetal and Neonatal Medicine, C. Arrigo Children's Hospital Alessandria, 15100 Alessandria, Italy.
Antonio D W GavilanesDepartment of Pediatrics, Neonatology and Child Neurology, Maastricht University, 6200 MD Maastricht, The Netherlands.
Luc J ZimmermannDepartment of Pediatrics, Neonatology and Child Neurology, Maastricht University, 6200 MD Maastricht, The Netherlands.
Hans J S VlesDepartment of Pediatrics, Neonatology and Child Neurology, Maastricht University, 6200 MD Maastricht, The Netherlands.
Diego GazzoloNeonatal Intensive Care Unit, Department of Pediatrics, University of Chieti, 65100 Chieti, Italy.
University of Chieti-Pescara · ITAzienda Sanitaria Locale Alessandria · ITIRCCS Policlinico San Donato · ITMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perioperative stress detection in children with congenital heart disease (CHD), particularly in the brain, is still limited. Among biomarkers, γ-amino-aminobutyric acid (GABA) assessment in biological fluids appears to be promising for its regulatory action on the cardiovascular and cerebral systems. We aimed to investigate cyanotic (C) or non-cyanotic (N) CHD children for GABA blood level changes in the perioperative period. We conducted an observational study in 68 CHD infants (C:

Indexed as

braincardiopulmonary by-passchildrencoolingGABAnewbornreoxygenation

Identifiers

PMID34202425
PMCPMC8304774
OpenAlexW3173651225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.