Evidence map›Paper›PMID 34202406›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Effects of Serine or Threonine in the Active Site of Typical 2-Cys Prx on Hyperoxidation Susceptibility and on Chaperone Activity.

Carlos A Tairum, Melina Cardoso Santos, Carlos Alexandre Breyer, Ana Laura Pires de Oliveira, Vitoria Isabela Montanhero Cabrera, Guilherme Toledo-Silva, Gustavo Maruyama Mori, Marcos Hikari Toyama, Luis Eduardo Soares Netto, Marcos Antonio de Oliveira

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Carlos A TairumInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 01049-010, Brazil.ORCID 0000-0003-2757-5907
Melina Cardoso SantosInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 01049-010, Brazil.ORCID 0000-0002-6458-8646
Carlos Alexandre BreyerInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 01049-010, Brazil.ORCID 0000-0002-3602-291X
Ana Laura Pires de OliveiraInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 01049-010, Brazil.
Vitoria Isabela Montanhero CabreraInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 01049-010, Brazil.ORCID 0000-0002-7271-9626
Guilherme Toledo-SilvaLaboratório de Biomarcadores de Contaminação Aquática e Imunoquímica, Departamento de Bioquímica, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil.ORCID 0000-0002-9953-2861
Gustavo Maruyama MoriLaboratório de Ecologia Molecular, Instituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 01049-010, Brazil.ORCID 0000-0003-2308-2224
Marcos Hikari ToyamaInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 01049-010, Brazil.ORCID 0000-0001-6836-3084
Luis Eduardo Soares NettoDepartamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo 01049-010, Brazil.ORCID 0000-0002-4250-9177
Marcos Antonio de OliveiraInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 01049-010, Brazil.ORCID 0000-0002-1192-7296
Universidade Estadual Paulista (Unesp) · BRUniversidade de São Paulo · BRUniversidade Federal de Santa Catarina · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2007/50930-3Fundação de Amparo à Pesquisa do Estado de São Paulo 2011/13500-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/07937-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/06263-4Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/19942-7Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/20291-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/12628-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/04054-4Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/02868-1
6 · The paper itself

Abstract

Typical 2-Cys peroxiredoxins (2-Cys Prx) are ubiquitous Cys-based peroxidases, which are stable as decamers in the reduced state, and may dissociate into dimers upon disulfide bond formation. A peroxidatic Cys (C

Indexed as

2-Cys Prxcatalytic triadchaperonehyperoxidationoligomerizationorganic hydroperoxides

Identifiers

PMID34202406
PMCPMC8300647
OpenAlexW3176725226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.