ReviewMolecules (Basel, Switzerland)2021
Antimicrobial Compounds Isolated from Endolichenic Fungi: A Review.
Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed.
- Genomic-Driven Identification of Conserved Biosynthetic Gene Clusters inMetabolites · 2026Article
- Bioprospecting of Endolichenic FungusIndian journal of microbiology · 2025Article
- Comparative Antagonistic Activities of Endolichenic Fungi Isolated from the Fruticose LichensJournal of fungi (Basel, Switzerland) · 2025Article
- Isolation, Chemical Characterization, and Antimicrobial Activity of Secondary Metabolites fromMolecules (Basel, Switzerland) · 2025Article
- Exploring bioactive molecules released during inter- and intraspecific competition: A paradigm for novel antiparasitic drug discovery and design for human use.Current research in parasitology & vector-borne diseases · 2025Review
- Additions of New Endolichenic Fungi to Herpotrichiellaceae (Chaetothyriales, Ascomycota) from northern Thailand.MycoKeys · 2025Article
- Structures and Biological Activities of Secondary Metabolites fromJournal of fungi (Basel, Switzerland) · 2024Review
- Steroids and Epicoccarines fromPhytochemistry letters · 2024Article
- A spectrophotometric analysis of extracted water-soluble phenolic metabolites of lichens.Planta · 2024Article
- Draft genome sequence of endolichenic fungusMicrobiology resource announcements · 2023Article
- (±) Pestalactone D and pestapyrone F, two new isocoumarins from an endolichenic Pestalotiopsis rhododendri.The Journal of antibiotics · 2023Article
- Assignment of Absolute Configurations of Two Promising Anti-Molecules (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
A lichen is a symbiotic relationship between a fungus and a photosynthetic organism, which is algae or cyanobacteria. Endolichenic fungi are a group of microfungi that resides asymptomatically within the thalli of lichens. Endolichenic fungi can be recognized as luxuriant metabolic artists that produce propitious bioactive secondary metabolites. More than any other time, there is a worldwide search for new antibiotics due to the alarming increase in microbial resistance against the currently available therapeutics. Even though a few antimicrobial compounds have been isolated from endolichenic fungi, most of them have moderate activities, implying the need for further structural optimizations. Recognizing this timely need and the significance of endolichenic fungi as a promising source of antimicrobial compounds, the activity, sources and the structures of 31 antibacterial compounds, 58 antifungal compounds, two antiviral compounds and one antiplasmodial (antimalarial) compound are summarized in this review. In addition, an overview of the common scaffolds and structural features leading to the corresponding antimicrobial properties is provided as an aid for future studies. The current challenges and major drawbacks of research related to endolichenic fungi and the remedies for them have been suggested.
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