Evidence map›Paper›PMID 34202232›Full record

ArticleBiomedicines2021

Lumbar Interbody Fusion Conducted on a Porcine Model with a Bioresorbable Ceramic/Biopolymer Hybrid Implant Enriched with Hyperstable Fibroblast Growth Factor 2.

Milan Krticka, Ladislav Planka, Lucy Vojtova, Vladimir Nekuda, Premysl Stastny, Radek Sedlacek, Adam Brinek, Michaela Kavkova, Eduard Gopfert, Vera Hedvicakova and 11 more

Abstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Speed and quality of interbody fusion in porous bioceramic AlJournal of orthopaedic surgery and research · 2023
    Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Milan KrtickaTrauma Surgery Department, Faculty of Medicine, Masaryk University and The University Hospital Brno, 625 00 Brno, Czech Republic.
Ladislav PlankaDepartment of Paediatric Surgery, Orthopedics and Traumatology, Faculty of Medicine, Masaryk University and The University Hospital Brno, 662 63 Brno, Czech Republic.
Lucy VojtovaCEITEC-Central European Institute of Technology, Brno University of Technology, 612 00 Brno, Czech Republic.ORCID 0000-0001-5281-7045
Vladimir NekudaTrauma Surgery Department, Faculty of Medicine, Masaryk University and The University Hospital Brno, 625 00 Brno, Czech Republic.
Premysl StastnyCEITEC-Central European Institute of Technology, Brno University of Technology, 612 00 Brno, Czech Republic.
Radek SedlacekDepartment of Mechanics, Biomechanics and Mechatronics, Faculty of Mechanical Engineering, Czech Technical University in Prague, 160 00 Prague, Czech Republic.ORCID 0000-0001-8468-5921
Adam BrinekCEITEC-Central European Institute of Technology, Brno University of Technology, 612 00 Brno, Czech Republic.
Michaela KavkovaCEITEC-Central European Institute of Technology, Brno University of Technology, 612 00 Brno, Czech Republic.
Eduard GopfertVeterinary Research Institute, 621 00 Brno, Czech Republic.
Vera HedvicakovaUniversity Center for Energy Efficient Buildings, Czech Technical University in Prague, 273 43 Bustehrad, Czech Republic.
Michala RampichovaUniversity Center for Energy Efficient Buildings, Czech Technical University in Prague, 273 43 Bustehrad, Czech Republic.ORCID 0000-0001-9608-3370
Leos KrenDepartment of Pathology, Faculty of Medicine of Masaryk University and The University Hospital Brno, 625 00 Brno, Czech Republic.
Kvetoslava LiskovaDepartment of Pathology, Faculty of Medicine of Masaryk University and The University Hospital Brno, 625 00 Brno, Czech Republic.
Daniel IraTrauma Surgery Department, Faculty of Medicine, Masaryk University and The University Hospital Brno, 625 00 Brno, Czech Republic.
Jana DorazilováCEITEC-Central European Institute of Technology, Brno University of Technology, 612 00 Brno, Czech Republic.ORCID 0000-0002-4072-8173
Tomas SuchyDepartment of Composites and Carbon Materials, Institute of Rock Structure and Mechanics, The Czech Academy of Sciences, 182 09 Prague, Czech Republic.
Tomas ZikmundCEITEC-Central European Institute of Technology, Brno University of Technology, 612 00 Brno, Czech Republic.
Jozef KaiserCEITEC-Central European Institute of Technology, Brno University of Technology, 612 00 Brno, Czech Republic.ORCID 0000-0002-7397-125X
David StaryDepartment of Paediatric Surgery, Orthopedics and Traumatology, Faculty of Medicine, Masaryk University and The University Hospital Brno, 662 63 Brno, Czech Republic.
Martin FaldynaVeterinary Research Institute, 621 00 Brno, Czech Republic.ORCID 0000-0002-5448-7235
Martin TrunecCEITEC-Central European Institute of Technology, Brno University of Technology, 612 00 Brno, Czech Republic.

Funding

Ministerstvo Zdravotnictví Ceské Republiky 17-31276A
6 · The paper itself

Abstract

Many growth factors have been studied as additives accelerating lumbar fusion rates in different animal models. However, their low hydrolytic and thermal stability both in vitro and in vivo limits their workability and use. In the proposed work, a stabilized vasculogenic and prohealing fibroblast growth factor-2 (FGF2-STAB

Indexed as

animal modelautograftbiomechanicsceramiccollagenFGF2histologylumbar spinal fusionmicro-CTtissue engineering

Identifiers

PMID34202232
PMCPMC8301420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.