Evidence map›Paper›PMID 34202096›Full record

ReviewJournal of personalized medicine2021

Radiomics in Lung Diseases Imaging: State-of-the-Art for Clinicians.

Anne-Noëlle Frix, François Cousin, Turkey Refaee, Fabio Bottari, Akshayaa Vaidyanathan, Colin Desir, Wim Vos, Sean Walsh, Mariaelena Occhipinti, Pierre Lovinfosse and 6 more

Abstract readReview
In one paragraph

Review in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Multi-omics to study chronic respiratory diseases and viral infections.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  8. Drug-Induced Interstitial Lung Disease in Lung Cancer Patients.Respiration; international review of thoracic diseases · 2026
    Review
  9. Article
  10. Article
  11. Radiomics and Artificial Intelligence in Pulmonary Fibrosis.Journal of imaging informatics in medicine · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Anne-Noëlle FrixDepartment of Respiratory Medicine, University Hospital of Liège, 4000 Liège, Belgium.
François CousinDepartment of Nuclear Medicine and Oncological Imaging, University Hospital of Liège, 4000 Liège, Belgium.
Turkey RefaeeThe D-Lab, Department of Precision Medicine, GROW-School for Oncology, Maastricht University, 6229 Maastricht, The Netherlands.ORCID 0000-0001-6605-1845
Fabio BottariResearch and Development, Radiomics, 4000 Liège, Belgium.
Akshayaa VaidyanathanThe D-Lab, Department of Precision Medicine, GROW-School for Oncology, Maastricht University, 6229 Maastricht, The Netherlands.
Colin DesirDepartment of Radiology, University Hospital of Liège, 4000 Liège, Belgium.
Wim VosResearch and Development, Radiomics, 4000 Liège, Belgium.
Sean WalshResearch and Development, Radiomics, 4000 Liège, Belgium.
Mariaelena OcchipintiResearch and Development, Radiomics, 4000 Liège, Belgium.
Pierre LovinfosseDepartment of Nuclear Medicine and Oncological Imaging, University Hospital of Liège, 4000 Liège, Belgium.
Ralph T H LeijenaarResearch and Development, Radiomics, 4000 Liège, Belgium.
Roland HustinxDepartment of Nuclear Medicine and Oncological Imaging, University Hospital of Liège, 4000 Liège, Belgium.
Paul MeunierDepartment of Radiology, University Hospital of Liège, 4000 Liège, Belgium.
Renaud LouisDepartment of Respiratory Medicine, University Hospital of Liège, 4000 Liège, Belgium.
Philippe LambinThe D-Lab, Department of Precision Medicine, GROW-School for Oncology, Maastricht University, 6229 Maastricht, The Netherlands.ORCID 0000-0001-7961-0191
Julien GuiotDepartment of Respiratory Medicine, University Hospital of Liège, 4000 Liège, Belgium.ORCID 0000-0001-7800-1730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) has increasingly been serving the field of radiology over the last 50 years. As modern medicine is evolving towards precision medicine, offering personalized patient care and treatment, the requirement for robust imaging biomarkers has gradually increased. Radiomics, a specific method generating high-throughput extraction of a tremendous amount of quantitative imaging data using data-characterization algorithms, has shown great potential in individuating imaging biomarkers. Radiomic analysis can be implemented through the following two methods: hand-crafted radiomic features extraction or deep learning algorithm. Its application in lung diseases can be used in clinical decision support systems, regarding its ability to develop descriptive and predictive models in many respiratory pathologies. The aim of this article is to review the recent literature on the topic, and briefly summarize the interest of radiomics in chest Computed Tomography (CT) and its pertinence in the field of pulmonary diseases, from a clinician's perspective.

Indexed as

artificial intelligencelung diseasesprecision medicineradiomics

Identifiers

PMID34202096
PMCPMC8306026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.