Evidence map›Paper›PMID 34201951›Full record

ReviewMarine drugs2021

Marine Actinomycetes, New Sources of Biotechnological Products.

Sveta V Jagannathan, Erika M Manemann, Sarah E Rowe, Maiya C Callender, William Soto

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 2 pooled it
17.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 2 syntheses or guidelines pooled it, 178 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Bioprospecting Indoor Bacteria Producing Bioactive Metabolites.Environmental microbiology reports · 2026
    Article
  5. Article
  6. Article
  7. Actinomycetes in the spotlight: biodiversity and their role in bioremediation.World journal of microbiology & biotechnology · 2026
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. New Marine Actinobacteria Strain,Microorganisms · 2025
    Article
  16. Antimicrobial Unusual Small Molecules from MarineInternational journal of molecular sciences · 2025
    Article
  17. Isolation of a NovelToxins · 2025
    Article
  18. Review
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sveta V JagannathanDepartment of Biology, College of William & Mary, Williamsburg, VA 23185, USA.ORCID 0000-0001-5393-0162
Erika M ManemannDepartment of Biology, College of William & Mary, Williamsburg, VA 23185, USA.ORCID 0000-0001-8577-1098
Sarah E RoweDepartment of Biology, College of William & Mary, Williamsburg, VA 23185, USA.ORCID 0000-0003-1083-8395
Maiya C CallenderDepartment of Biology, College of William & Mary, Williamsburg, VA 23185, USA.
William SotoDepartment of Biology, College of William & Mary, Williamsburg, VA 23185, USA.
William & Mary · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Actinomycetales order is one of great genetic and functional diversity, including diversity in the production of secondary metabolites which have uses in medical, environmental rehabilitation, and industrial applications. Secondary metabolites produced by actinomycete species are an abundant source of antibiotics, antitumor agents, anthelmintics, and antifungals. These actinomycete-derived medicines are in circulation as current treatments, but actinomycetes are also being explored as potential sources of new compounds to combat multidrug resistance in pathogenic bacteria. Actinomycetes as a potential to solve environmental concerns is another area of recent investigation, particularly their utility in the bioremediation of pesticides, toxic metals, radioactive wastes, and biofouling. Other applications include biofuels, detergents, and food preservatives/additives. Exploring other unique properties of actinomycetes will allow for a deeper understanding of this interesting taxonomic group. Combined with genetic engineering, microbial experimental evolution, and other enhancement techniques, it is reasonable to assume that the use of marine actinomycetes will continue to increase. Novel products will begin to be developed for diverse applied research purposes, including zymology and enology. This paper outlines the current knowledge of actinomycete usage in applied research, focusing on marine isolates and providing direction for future research.

Indexed as

ActinobacteriaAquatic OrganismsBiotechnologyHumansactinomycetesindustrial microbiologymicrobial experimental evolution

Identifiers

PMID34201951
PMCPMC8304352
OpenAlexW3173455641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.