Evidence map›Paper›PMID 34201946›Full record

ArticleJournal of clinical medicine2021

Adiponectin Associates with Rheumatoid Arthritis Risk in Overweight and Obesity Independently of Other Adipokines.

Yuan Zhang, Linda Johansson, Johanna Andersson-Assarsson, Magdalena Taube, Markku Peltonen, Per-Arne Svensson, Christian Herder, Anna Rudin, Lena Carlsson, Solbritt Rantapää-Dahlqvist and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Organokines in Rheumatoid Arthritis: A Critical Review.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Yuan ZhangDepartment of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, SE-40530 Gothenburg, Sweden.
Linda JohanssonPublic Health and Clinical Medicine/Rheumatology, Umeå University, SE-90587 Umeå, Sweden.ORCID 0000-0001-7071-4699
Johanna Andersson-AssarssonDepartment of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, SE-41345 Gothenburg, Sweden.ORCID 0000-0001-9082-8589
Magdalena TaubeDepartment of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, SE-41345 Gothenburg, Sweden.
Markku PeltonenPublic Health Promotion Unit, National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
Per-Arne SvenssonDepartment of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, SE-41345 Gothenburg, Sweden.
Christian HerderInstitute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich-Heine University Duesseldorf, 40225 Duesseldorf, Germany.ORCID 0000-0002-2050-093X
Anna RudinDepartment of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, SE-40530 Gothenburg, Sweden.
Lena CarlssonDepartment of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, SE-41345 Gothenburg, Sweden.
Solbritt Rantapää-DahlqvistPublic Health and Clinical Medicine/Rheumatology, Umeå University, SE-90587 Umeå, Sweden.ORCID 0000-0001-8259-3863
Cristina MaglioDepartment of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, SE-40530 Gothenburg, Sweden.ORCID 0000-0002-3786-5767
University of Gothenburg · SEUmeå University · SEDüsseldorf University Hospital · DEKarolinska Institutet · SESahlgrenska University Hospital · SEWallenberg Wood Science Center · SE

Funding

King Gustaf V's 80-Year Fund noneKing Gustaf V's and Queen Victoria's Fund noneKnut och Alice Wallenbergs Stiftelse grant 2016/4839Ministry of Culture and Science of the State of North Rhine-Westphalia noneSahlgrenska University Hospital Regional Agreement on Medical Education and Research grants nonethe German Federal Ministry of Education and Research nonethe German Federal Ministry of Health nonethe Swedish Rheumatism Association noneUmeå University noneVetenskapsrådet K2013-52X-20307-07-3 and Dnr:2018-02551
6 · The paper itself

Abstract

We recently reported that increased serum adiponectin was associated with rheumatoid arthritis (RA) risk in subjects with obesity. We hereby aim to determine if other adipokines associate with RA risk and if the association between adiponectin and RA is independent of other adipokines. Two nested-case control studies were performed in two different cohorts: 82 participants of the Swedish Obese Subjects (SOS) study who developed RA during follow-up matched with 410 controls, and 88 matched pairs from the Medical Biobank of Northern Sweden. Baseline levels of circulating adipokines were measured using ELISA. In a multivariable analysis in the SOS cohort, higher adiponectin was associated with an increased risk of RA independently of other adipokines (OR for RA risk: 1.06, 95% CI: 1.01-1.12,

Indexed as

adipokinesadiponectincase control studyobesityoverweightrheumatology

Identifiers

PMID34201946
PMCPMC8267689
OpenAlexW3173387325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.