Evidence map›Paper›PMID 34201916›Full record

ArticleBiomolecules2021

Interhelical H-Bonds Modulate the Activity of a Polytopic Transmembrane Kinase.

Juan Cruz Almada, Ana Bortolotti, Jean Marie Ruysschaert, Diego de Mendoza, María Eugenia Inda, Larisa Estefanía Cybulski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Folding and Insertion of Transmembrane Helices at the ER.International journal of molecular sciences · 2021
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juan Cruz AlmadaDepartamento de Microbiología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario-Argentine National Research Council-CONICET, Suipacha 531, Rosario 2000, Argentina.ORCID 0000-0001-6107-1572
Ana BortolottiDepartamento de Microbiología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario-Argentine National Research Council-CONICET, Suipacha 531, Rosario 2000, Argentina.
Jean Marie RuysschaertLaboratory for the Structure and Function of Biological Membranes, Center for Structural Biology and Bioinformatics, Université Libre de Bruxelles, CP 206/2, Bd du Triomphe, 1050 Brussels, Belgium.
Diego de MendozaLaboratorio de Fisiología Microbiana, Instituto de Biología Molecular y Celular de Rosario (IBR), CONICET, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Ocampo y Esmeralda, Predio CONICET Rosario, Rosario 2000, Argentina.
María Eugenia IndaDepartamento de Microbiología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario-Argentine National Research Council-CONICET, Suipacha 531, Rosario 2000, Argentina.
Larisa Estefanía CybulskiDepartamento de Microbiología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario-Argentine National Research Council-CONICET, Suipacha 531, Rosario 2000, Argentina.ORCID 0000-0003-1573-3541

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DesK is a Histidine Kinase that allows

Indexed as

Amino Acid SequenceBacillus subtilisBacterial ProteinsHistidine KinaseHydrogen BondingProtein TransportBacterial ProteinsHistidine Kinasedimerisation motifhistidine kinasehydrogen bond interactionreceptorsignal transductiontransmembrane protein interactions

Identifiers

PMID34201916
PMCPMC8301901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.