Evidence map›Paper›PMID 34201875›Full record

ArticleMolecules (Basel, Switzerland)2021

Rosin Derivatives as a Platform for the Antiviral Drug Design.

Larisa Popova, Olga Ivanchenko, Evgeniia Pochkaeva, Sergey Klotchenko, Marina Plotnikova, Angelica Tsyrulnikova, Ekaterina Aronova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Multipronged Approach to Profiling Metabolites inFoods (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Larisa PopovaGraduate School of Biotechnology and Food Science, Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya Street 29, 195251 Saint Petersburg, Russia.
Olga IvanchenkoGraduate School of Biotechnology and Food Science, Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya Street 29, 195251 Saint Petersburg, Russia.
Evgeniia PochkaevaGraduate School of Biotechnology and Food Science, Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya Street 29, 195251 Saint Petersburg, Russia.
Sergey KlotchenkoSmorodintsev Research Institute of Influenza, Prof. Popov Street 15/17, 197376 Saint Petersburg, Russia.ORCID 0000-0003-0289-6560
Marina PlotnikovaSmorodintsev Research Institute of Influenza, Prof. Popov Street 15/17, 197376 Saint Petersburg, Russia.ORCID 0000-0001-8196-3156
Angelica TsyrulnikovaGraduate School of Biotechnology and Food Science, Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya Street 29, 195251 Saint Petersburg, Russia.ORCID 0000-0003-1413-220X
Ekaterina AronovaGraduate School of Biotechnology and Food Science, Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya Street 29, 195251 Saint Petersburg, Russia.
Peter the Great St. Petersburg Polytechnic University · RUResearch Institute of Influenza · RU

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2020-934 dated 17.11.2020
6 · The paper itself

Abstract

The increased complexity due to the emergence and rapid spread of new viral infections prompts researchers to search for potential antiviral and protective agents for mucous membranes among various natural objects, for example, plant raw materials, their individual components, as well as the products of their chemical modification. Due to their structure, resin acids are valuable raw materials of natural origin to synthesize various bioactive substances. Therefore, the purpose of this study was to confirm the possibility of using resin acid derivatives for the drug design. As a result, we studied the cytotoxicity and biological activity of resin acid derivatives. It was shown that a slight decrease in the viral load in the supernatants was observed upon stimulation of cells (

Indexed as

A549 CellsAnti-Bacterial AgentsAntifungal AgentsAntiviral AgentsBacillus subtilisCandida tropicalisCell SurvivalDrug DesignEscherichia coliHumansInfluenza, HumanOrthomyxoviridaeResins, PlantStructure-Activity RelationshipAnti-Bacterial AgentsAntifungal AgentsAntiviral AgentsResins, Plantrosinantibacterial activityantiviral activitybiological activitycytotoxicityDAAfungicidal activityMTT assayPASS-online modelingSWISS-ADME web server

Identifiers

PMID34201875
PMCPMC8270270
OpenAlexW3175694290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.