Evidence map›Paper›PMID 34201869›Full record

ArticleViruses2021

Exploring Codon Adjustment Strategies towards

Hasan Arsın, Andrius Jasilionis, Håkon Dahle, Ruth-Anne Sandaa, Runar Stokke, Eva Nordberg Karlsson, Ida Helene Steen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Bacterial natural product discovery by heterologous expression.Journal of industrial microbiology & biotechnology · 2023
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Hasan ArsınDepartment of Biological Sciences, University of Bergen, N-5020 Bergen, Norway.
Andrius JasilionisDivision of Biotechnology, Lund University, P.O. Box 124, SE-221 00 Lund, Sweden.
Håkon DahleCentre for Deep Sea Research, University of Bergen, N-5020 Bergen, Norway.
Ruth-Anne SandaaDepartment of Biological Sciences, University of Bergen, N-5020 Bergen, Norway.
Runar StokkeDepartment of Biological Sciences, University of Bergen, N-5020 Bergen, Norway.ORCID 0000-0002-6056-7119
Eva Nordberg KarlssonDivision of Biotechnology, Lund University, P.O. Box 124, SE-221 00 Lund, Sweden.ORCID 0000-0002-8597-7050
Ida Helene SteenDepartment of Biological Sciences, University of Bergen, N-5020 Bergen, Norway.
University of Bergen · NOLund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine viral sequence space is immense and presents a promising resource for the discovery of new enzymes interesting for research and biotechnology. However, bottlenecks in the functional annotation of viral genes and soluble heterologous production of proteins hinder access to downstream characterization, subsequently impeding the discovery process. While commonly utilized for the heterologous expression of prokaryotic genes, codon adjustment approaches have not been fully explored for viral genes. Herein, the sequence-based identification of a putative prophage is reported from within the genome of

Indexed as

Cloning, MolecularCodonEscherichia coliFusobacteriaGenome, ViralHydrothermal VentsMultigene FamilyPhylogenyProphagesProtein FoldingProtein StabilityRecombinant ProteinsSiphoviridaeTransition TemperatureViral ProteinsCodonRecombinant ProteinsViral Proteinscodon harmonizationcodon optimizationEscherichia coliheterologous expressionhydrothermal ventHypnocyclicus thermotrophuslytic cassetteprophage

Identifiers

PMID34201869
PMCPMC8310279
OpenAlexW3176316387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.