Evidence map›Paper›PMID 34201868›Full record

ArticleJournal of clinical medicine2021

Understanding COVID-19 Epidemiology and Implications for Control: The Experience from a Greek Semi-Closed Community.

Ourania S Kotsiou, Dimitrios Papagiannis, Evangelos C Fradelos, Garyfallia Perlepe, Angeliki Miziou, Dimitra S Siachpazidou, Konstantinos I Gourgoulianis

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Long-Term Impact of COVID-19 Pandemic in Sleep Quality and Lifestyle in Young Adults.International journal of environmental research and public health · 2022
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ourania S KotsiouFaculty of Nursing, School of Health Sciences, University of Thessaly, GAIOPOLIS, 41110 Larissa, Greece.ORCID 0000-0001-5219-6971
Dimitrios PapagiannisPublic Health & Vaccines Lab, Department of Nursing, School of Health Sciences, University of Thessaly, GAIOPOLIS, 41110 Larissa, Greece.
Evangelos C FradelosFaculty of Nursing, School of Health Sciences, University of Thessaly, GAIOPOLIS, 41110 Larissa, Greece.ORCID 0000-0003-0244-9760
Garyfallia PerlepeDepartment of Respiratory Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, BIOPOLIS, 41110 Larissa, Greece.
Angeliki MiziouDepartment of Respiratory Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, BIOPOLIS, 41110 Larissa, Greece.
Dimitra S SiachpazidouDepartment of Respiratory Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, BIOPOLIS, 41110 Larissa, Greece.ORCID 0000-0002-7688-8072
Konstantinos I GourgoulianisDepartment of Respiratory Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, BIOPOLIS, 41110 Larissa, Greece.ORCID 0000-0001-9541-1010

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to estimate the SARS-CoV-2 antigen and antibody seroprevalence in one of the worst-affected by the pandemic semi-closed communities in Greece, Deskati, and evaluate the sociodemographic and clinical correlations of functional antibody responses.

methodsThe Ag2019n-CoV V1310/V1330 Rapid Test (Prognosis Biotech, Greece) was used for antigen detection. The Rapid Test 2019-nCoV Total Ig, V1210/V1230 (Prognosis Biotech, Greece), and the SARS-CoV-2 IgG II Quant method (Architect, Abbott, Illinois, USA) were used for antibody testing.

resultsNone of the participants had a positive antigen result. SARS-CoV-2 seropositivity ranged from 13% to 45% in the study population, depending on the method. One-third of the participants with known past infection had a positive antibody test result 77 ± 13 days after infection. Two-fifths of infections determined by serology were asymptomatic. The advancing age and hospitalization predicted seropositivity among patients with past infection. Half of the participants who tested positive for antibodies were not aware of past infection.

conclusionsHigh-burden contexts in Greece, such as Deskati, are not so far from herd immunity thresholds. We highlighted the value of low-cost serosurveys targeting both symptomatic and asymptomatic populations to evaluate the natural immune response to SARS-CoV-2 in nonvaccinated susceptibles and design evidence-based policies for lifting lockdowns.

Indexed as

coronavirussemi-closed communityseroprevalence

Identifiers

PMID34201868
PMCPMC8268522

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.