Evidence map›Paper›PMID 34201784›Full record

ReviewPharmaceutics2021

Review of Pharmacokinetics and Pharmacogenetics in Atypical Long-Acting Injectable Antipsychotics.

Francisco José Toja-Camba, Nerea Gesto-Antelo, Olalla Maroñas, Eduardo Echarri Arrieta, Irene Zarra-Ferro, Miguel González-Barcia, Enrique Bandín-Vilar, Victor Mangas Sanjuan, Fernando Facal, Manuel Arrojo Romero and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Francisco José Toja-CambaPharmacy Department, University Clinical Hospital of Ourense (SERGAS), Ramón Puga 52, 32005 Ourense, Spain.ORCID 0000-0002-7768-9358
Nerea Gesto-AnteloGenomic Medicine Group, CIMUS, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Olalla MaroñasGenomic Medicine Group, CIMUS, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Eduardo Echarri ArrietaPharmacy Department, University Clinical Hospital of Santiago de Compostela (SERGAS), 15706 Santiago de Compostela, Spain.
Irene Zarra-FerroClinical Pharmacology Group, Institute of Health Research (IDIS), Travesía da Choupana s/n, 15706 Santiago de Compostela, Spain.
Miguel González-BarciaClinical Pharmacology Group, Institute of Health Research (IDIS), Travesía da Choupana s/n, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-8231-7831
Enrique Bandín-VilarClinical Pharmacology Group, Institute of Health Research (IDIS), Travesía da Choupana s/n, 15706 Santiago de Compostela, Spain.ORCID 0000-0001-5775-0900
Victor Mangas SanjuanClinical Pharmacology Group, Institute of Health Research (IDIS), Travesía da Choupana s/n, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-3388-5023
Fernando FacalPsychiatry Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Travesía da Choupana s/n, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-1157-6772
Manuel Arrojo RomeroPsychiatry Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Travesía da Choupana s/n, 15706 Santiago de Compostela, Spain.
Angel CarracedoGenomic Medicine Group, CIMUS, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0003-1085-8986
Cristina Mondelo-GarcíaClinical Pharmacology Group, Institute of Health Research (IDIS), Travesía da Choupana s/n, 15706 Santiago de Compostela, Spain.ORCID 0000-0001-8555-1415
Anxo Fernández-FerreiroClinical Pharmacology Group, Institute of Health Research (IDIS), Travesía da Choupana s/n, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-7348-7337
Universidade de Santiago de Compostela · ESServicio Gallego de Salud · ESUniversitat de València · ES

Funding

Instituto de Salud Carlos III CM20/00135Instituto de Salud Carlos III JR18/00014Instituto de Salud Carlos III JR20/00026
6 · The paper itself

Abstract

Over the last two decades, pharmacogenetics and pharmacokinetics have been increasingly used in clinical practice in Psychiatry due to the high variability regarding response and side effects of antipsychotic drugs. Specifically, long-acting injectable (LAI) antipsychotics have different pharmacokinetic profile than oral formulations due to their sustained release characteristics. In addition, most of these drugs are metabolized by

Indexed as

antipsychoticsaripiprazoleCYP2D6LAIpaliperidonepharmacogeneticspopulation pharmacokinetic modelsrisperidone

Identifiers

PMID34201784
PMCPMC8308912
OpenAlexW3173484686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.