Evidence map›Paper›PMID 34201686›Full record

Trial reportToxins2021

Effect of Combined Bee Venom Acupuncture and NSAID Treatment for Non-Specific Chronic Neck Pain: A Randomized, Assessor-Blinded, Pilot Clinical Trial.

Boram Lee, Byung-Kwan Seo, O-Jin Kwon, Dae-Jean Jo, Jun-Hwan Lee, Sanghun Lee

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Boram LeeClinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.ORCID 0000-0003-1679-0644
Byung-Kwan SeoDepartment of Acupuncture & Moxibustion, Kyung Hee University Hospital at Gangdong, Seoul 05278, Korea.ORCID 0000-0002-3356-2355
O-Jin KwonClinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.ORCID 0000-0002-7349-4596
Dae-Jean JoDepartment of Neurosurgery, Kyung Hee University Hospital at Gangdong, Seoul 05278, Korea.
Jun-Hwan LeeClinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.ORCID 0000-0001-5730-6869
Sanghun LeeKorean Medicine Life Science, Campus of Korea Institute of Oriental Medicine, University of Science & Technology (UST), Daejeon 34054, Korea.ORCID 0000-0001-7124-6874
Korea Institute of Oriental Medicine · KRKyung Hee University Hospital at Gangdong · KR

Funding

a Daejeon Technopark grant; Development of Public Healthcare System for Citizens through Traditional Korean Medicine G12050Korea Institute of Oriental Medicine KSN2021210
6 · The paper itself

Abstract

This study aimed to investigate the feasibility of a combined treatment of bee venom acupuncture (BVA) and non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of non-specific chronic neck pain (NCNP). Patients with NCNP for ≥3 months were randomly allocated to a BVA, NSAIDs, or combined group (1:1:1), receiving 6 sessions of BVA, loxoprofen (180 mg daily), or a combination, respectively, for 3 weeks. Recruitment, adherence, and completion rates were calculated to assess feasibility. Bothersomeness, pain, disability, quality of life, depressive status, treatment credibility, and adverse events were assessed. In total, 60 participants were enrolled, and 54 completed the trial. Recruitment, adherence, and completion rates were 100%, 95%, and 90%, respectively. Bothersomeness, pain, disability, and depressive symptoms significantly improved in all groups after treatment (

Indexed as

Acupuncture TherapyAdultAnti-Inflammatory Agents, Non-SteroidalBee VenomsChronic PainCombined Modality TherapyFemaleHumansMaleMiddle AgedNeck PainPhenylpropionatesQuality of LifeSingle-Blind MethodTreatment OutcomeAnti-Inflammatory Agents, Non-SteroidalBee VenomsloxoprofenPhenylpropionatesbee venom acupuncturenon-specific chronic neck painpharmacopuncturerandomized controlled trial

Identifiers

PMID34201686
PMCPMC8309931
OpenAlexW3175027251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.