Evidence map›Paper›PMID 34201567›Full record

ArticlePharmaceutics2021

Poly(l-Lactic Acid)-co-poly(Butylene Adipate) New Block Copolymers for the Preparation of Drug-Loaded Long Acting Injectable Microparticles.

Vasiliki Karava, Aggeliki Siamidi, Marilena Vlachou, Evi Christodoulou, Nikolaos D Bikiaris, Alexandra Zamboulis, Margaritis Kostoglou, Eleni Gounari, Panagiotis Barmpalexis

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Vasiliki KaravaDepartment of Pharmacy, Section of Pharmaceutical Technology, Zografou Campus, National and Kapodistrian University of Athens, 15784 Athens, Greece.
Aggeliki SiamidiDepartment of Pharmacy, Section of Pharmaceutical Technology, Zografou Campus, National and Kapodistrian University of Athens, 15784 Athens, Greece.ORCID 0000-0002-8664-408X
Marilena VlachouDepartment of Pharmacy, Section of Pharmaceutical Technology, Zografou Campus, National and Kapodistrian University of Athens, 15784 Athens, Greece.ORCID 0000-0002-2927-705X
Evi ChristodoulouDepartment of Chemistry, Laboratory of Polymer Chemistry and Technology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-2730-0778
Nikolaos D BikiarisDepartment of Chemistry, Laboratory of Polymer Chemistry and Technology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Alexandra ZamboulisDepartment of Chemistry, Laboratory of Polymer Chemistry and Technology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-1608-0773
Margaritis KostoglouLaboratory of Chemical and Environmental Technology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Eleni GounariBiohellenika Biotechnology Company, Leoforos Georgikis Scholis 65, 57001 Thessaloniki, Greece.ORCID 0000-0002-8263-5063
Panagiotis BarmpalexisDepartment of Pharmaceutical Technology, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-6765-512X
Aristotle University of Thessaloniki · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study evaluates the use of newly synthesized poly(l-lactic acid)-co-poly(butylene adipate) (PLA/PBAd) block copolymers as microcarriers for the preparation of aripiprazole (ARI)-loaded long acting injectable (LAI) formulations. The effect of various PLA to PBAd ratios (95/5, 90/10, 75/25 and 50/50

Indexed as

aripiprazoleblock copolymerslong acting injectablesmicroparticlespoly(butylene adipate)poly(l-lactic acid)sustained release

Identifiers

PMID34201567
PMCPMC8308927
OpenAlexW3174503652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.