ReviewViruses2021
Neurotropic Astroviruses in Animals.
Review in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Molecular characterization and evolutionary analysis of a duck astrovirus type 3 strain.Poultry science · 2026Article
- Discovery and rescue of porcine bastroviruses associated with polioencephalomyelitis in domestic pigs.Journal of virology · 2025Article
- Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization.Journal of virology · 2025Article
- Gut Virome of Tibetan Pigs Reveals the Diversity, Composition, and Distribution of Potential Novel Viruses/Variants.Transboundary and emerging diseases · 2025Article
- Article
- Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization.bioRxiv : the preprint server for biology · 2024Article
- Porcine Astrovirus Infection in Brains of Pigs in Korea.Viruses · 2024Article
- Mouse and human immune responses share neutralization epitopes of HAstV-VA1.Journal of virology · 2024Article
- Article
- Assessing the Prevalence of Astroviruses in Water Environments: A Systematic Review and Meta-analysis.ACS ES&T water · 2023Review
- Temporal and coevolutionary analyses reveal the events driving the emergence and circulation of human mamastroviruses.Emerging microbes & infections · 2023Article
- Identification of a novel astrovirus from intestinal tissue of a donkey foal with severe diarrhea in China.Zoological research · 2023Article
- Detection and Genetic Characterization of Astroviruses in Brain Tissues of Wild Raccoon Dogs.Viruses · 2023Article
- Diversity and Genetic Characteristics of Astroviruses from Animals in Yunnan Province.Viruses · 2022Article
- Diversity of Astrovirus in Goats in Southwest China and Identification of Two Novel Caprine Astroviruses.Microbiology spectrum · 2022Article
- Bovine Astrovirus-A Comprehensive Review.Viruses · 2022Review
- A novel enterovirus in lambs with poliomyelitis and brain stem encephalitis.Transboundary and emerging diseases · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Astrovirus infections are among the main causes of diarrhea in children, but their significance for animal health has remained underestimated and largely unknown. This is changing due to the increasing amount of newly identified neurotropic astroviruses in cases of nonsuppurative encephalitis and neurological disease in humans, pigs, ruminant species and minks. Neurological cases in ruminants and humans usually occur sporadically and as isolated cases. This contrasts with the situation in pigs and minks, in which diseases associated with neurotropic astroviruses are endemic and occur on the herd level. Affected animals show neurological signs such as mild ataxia to tetraplegia, loss of orientation or trembling, and the outcome is often fatal. Non-suppurative inflammation with perivascular cuffing, gliosis and neuronal necrosis are typical histological lesions of astrovirus encephalitis. Since astroviruses primarily target the gastrointestinal tract, it is assumed that they infect the brain through the circulatory system or retrograde following the nerves. The phylogenetic analysis of neurotropic astroviruses has revealed that they are genetically closely related, suggesting the presence of viral determinants for tissue tropism and neuroinvasion. In this review, we summarize the current knowledge on neurotropic astrovirus infections in animals and propose future research activities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.