Evidence map›Paper›PMID 34201458›Full record

ArticleNutrients2021

Effect of Preoperative Immunonutrition on Postoperative Major Morbidity after Cytoreductive Surgery and HIPEC in Patients with Peritoneal Metastasis.

Alba Fernández-Candela, Alicia Calero, Luís Sánchez-Guillén, Javier Escrig-Sos, José A Barreras, Francisco López-Rodríguez-Arias, Laura Armañanzas, Ana Murcia, Antonio Arroyo, Francisco Javier Lacueva

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Alba Fernández-CandelaPeritoneal Carcinomatosis Unit, General Surgery Department, Elche University General Hospital, 03202 Elche, Spain.ORCID 0000-0003-4213-8836
Alicia CaleroPeritoneal Carcinomatosis Unit, General Surgery Department, Elche University General Hospital, 03202 Elche, Spain.
Luís Sánchez-GuillénPeritoneal Carcinomatosis Unit, General Surgery Department, Elche University General Hospital, 03202 Elche, Spain.ORCID 0000-0003-0623-9074
Javier Escrig-SosDepartment of Medicine, University Jaume I (UJI), 12004 Valencia, Spain.
José A BarrerasPeritoneal Carcinomatosis Unit, General Surgery Department, Elche University General Hospital, 03202 Elche, Spain.
Francisco López-Rodríguez-AriasPeritoneal Carcinomatosis Unit, General Surgery Department, Elche University General Hospital, 03202 Elche, Spain.ORCID 0000-0001-9786-2659
Laura ArmañanzasPeritoneal Carcinomatosis Unit, General Surgery Department, Elche University General Hospital, 03202 Elche, Spain.ORCID 0000-0002-6708-7185
Ana MurciaPharmacy Department, Elche University General Hospital, 03202 Elche, Spain.ORCID 0000-0002-0165-0035
Antonio ArroyoPeritoneal Carcinomatosis Unit, General Surgery Department, Elche University General Hospital, 03202 Elche, Spain.ORCID 0000-0003-0157-5175
Francisco Javier LacuevaPeritoneal Carcinomatosis Unit, General Surgery Department, Elche University General Hospital, 03202 Elche, Spain.
Hospital General Universitario de Elche · ESUniversitat de Miguel Hernández d'Elx · ESUniversitat Jaume I · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of preoperative immunonutrition intake on postoperative major complications in patients following cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (HIPEC) was assessed. The accuracy of C-Reactive Protein (CRP) for detecting postoperative complications was also analyzed. Patients treated within a peritoneal carcinomatosis program in which a complete or optimal cytoreduction was achieved were retrospectively analyzed. They were divided into two groups based on whether preoperative immunonutrition (IMN) or not (non-IMN) were administered. Clinical and surgical variables and postoperative complications were gathered. Predictive values of major morbidity of CRP during the first 3 postoperative days (POD) were also evaluated. A total of 107 patients were included, 48 belonging to the IMN group and 59 to the non-IMN group. In multivariate analysis immunonutrition (OR 0.247; 95%CI 0.071-0.859;

Indexed as

Nutritional Physiological PhenomenaPostoperative CarePreoperative CareAgedArea Under CurveC-Reactive ProteinCytoreduction Surgical ProceduresFemaleHumansHyperthermic Intraperitoneal ChemotherapyLogistic ModelsMaleMiddle AgedMorbidityPeritoneal NeoplasmsPostoperative ComplicationsC-Reactive ProteinC-reactive proteincytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC)immunonutritionperitoneal carcinomatosisperitoneal metastasispostoperative complications

Identifiers

PMID34201458
PMCPMC8308234
OpenAlexW3176316537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.