Evidence map›Paper›PMID 34201399›Full record

ArticleJournal of personalized medicine2021

Non-Syndromic Dentinogenesis Imperfecta Caused by Mild Mutations in

Yejin Lee, Youn Jung Kim, Hong-Keun Hyun, Jae-Cheoun Lee, Zang Hee Lee, Jung-Wook Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. The genetics of non-syndromic dentinogenesis imperfecta: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Translated MutantJournal of personalized medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yejin LeeDepartment of Pediatric Dentistry, School of Dentistry & DRI, Seoul National University, Seoul 03080, Korea.
Youn Jung KimDepartment of Molecular Genetics, School of Dentistry & DRI, Seoul National University, Seoul 03080, Korea.
Hong-Keun HyunDepartment of Pediatric Dentistry, School of Dentistry & DRI, Seoul National University, Seoul 03080, Korea.ORCID 0000-0003-3478-3210
Jae-Cheoun LeeSeoul Chungdam Children's Dental Center, Seoul 06072, Korea.
Zang Hee LeeDepartment of Cell and Developmental Biology, School of Dentistry & DRI, Seoul National University, Seoul 03080, Korea.
Jung-Wook KimDepartment of Pediatric Dentistry, School of Dentistry & DRI, Seoul National University, Seoul 03080, Korea.ORCID 0000-0002-9399-2197
Seoul National University · KR

Funding

National Research Foundation of Korea NRF-2018R1A5A2024418 and NRF-2020R1A2C2100543
6 · The paper itself

Abstract

Hereditary dentin defects can be categorized as a syndromic form predominantly related to osteogenesis imperfecta (OI) or isolated forms without other non-oral phenotypes. Mutations in the gene encoding dentin sialophosphoprotein (DSPP) have been identified to cause dentinogenesis imperfecta (DGI) Types II and III and dentin dysplasia (DD) Type II. While DGI Type I is an OI-related syndromic phenotype caused mostly by monoallelic mutations in the genes encoding collagen type I alpha 1 chain (

Indexed as

COL1A2dentinogenesis imperfectadiscolorationhereditaryisolated dentin defectmutational hotspottooth

Identifiers

PMID34201399
PMCPMC8229930
OpenAlexW3170498008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.