Evidence map›Paper›PMID 34201266›Full record

ArticleMaterials (Basel, Switzerland)2021

Breast Cancer Inhibition by Biosynthesized Titanium Dioxide Nanoparticles Is Comparable to Free Doxorubicin but Appeared Safer in BALB/c Mice.

Haroon Iqbal, Anam Razzaq, Bushra Uzair, Noor Ul Ain, Shamaila Sajjad, Norah Ayidh Althobaiti, Aishah Eid Albalawi, Bouzid Menaa, Muhammad Haroon, Muslim Khan and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Application of nanoparticles in breast cancer treatment: a systematic review.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Pooled it
  3. Amine-Functionalized and Gold-Decorated Amine-Functionalized TiOInternational journal of molecular sciences · 2026
    Article
  4. Article
  5. Article
  6. Green Synthesis of Metal Nanoparticles UsingNanotechnology, science and applications · 2025
    Review
  7. Article
  8. Green synthesis of Zn-doped TIOBMC plant biology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Lithium: A Promising Anticancer Agent.Life (Basel, Switzerland) · 2023
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Haroon IqbalCollege of Pharmaceutical Science, Soochow University, Suzhou 215123, China.ORCID 0000-0002-7908-8804
Anam RazzaqCollege of Pharmaceutical Science, Soochow University, Suzhou 215123, China.
Bushra UzairDepartment of Biological Sciences, International Islamic University, Islamabad 44000, Pakistan.ORCID 0000-0003-2181-6378
Noor Ul AinCollege of Pharmaceutical Science, Soochow University, Suzhou 215123, China.ORCID 0000-0003-0423-2661
Shamaila SajjadDepartment of Biological Sciences, International Islamic University, Islamabad 44000, Pakistan.
Norah Ayidh AlthobaitiDepartment of Biology, Faculty of Science and Humanities, Shaqra University, Al-Quwayiyah 11961, Saudi Arabia.ORCID 0000-0001-6893-5521
Aishah Eid AlbalawiDepartment of Biology, Faculty of Sciences, University of Tabuk, Tabuk 47731, Saudi Arabia.ORCID 0000-0002-7695-8691
Bouzid MenaaDepartment of Oncology and Nanomedicine, California Innovations Corporation, San Diego, CA 92037, USA.
Muhammad HaroonFaculty of Pharmacy, Gomal University, Dera Ismail Khan 29050, Pakistan.
Muslim KhanDepartment of Chemistry, Kohat University of Science and Technology, Kohat 26000, Pakistan.
Naveed Ullah KhanCollege of Pharmaceutical Science, Soochow University, Suzhou 215123, China.ORCID 0000-0002-3338-1642
Farid MenaaDepartment of Oncology and Nanomedicine, California Innovations Corporation, San Diego, CA 92037, USA.ORCID 0000-0002-0258-7322
Soochow University · CNCalifornia Medical Innovations Institute · USInternational Islamic University, Islamabad · PKGomal University · PKKohat University of Science and Technology · PKShaqra University · SAUniversity of Tabuk · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer remains a global health burden prompting affordable, target-oriented, and safe chemotherapeutic agents to reduce its incidence rate worldwide. In this study, a rapid, cost-effective, and green synthesis of titanium dioxide (TiO

Indexed as

apoptosisbreast cancercardiotoxicitycytotoxicitydoxorubicinreactive oxygen speciesTiO2 nanoparticlesZanthoxylum armatum leaf extract

Identifiers

PMID34201266
PMCPMC8229371
OpenAlexW3171255636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.