Evidence map›Paper›PMID 34201185›Full record

ArticleNutrients2021

The Effects of High-Protein Diet and Resistance Training on Glucose Control and Inflammatory Profile of Visceral Adipose Tissue in Rats.

Claudia Stela Medeiros, Ivo Vieira de Sousa Neto, Keemilyn Karla Santos Silva, Ana Paula Castro Cantuária, Taia Maria Berto Rezende, Octávio Luiz Franco, Rita de Cassia Marqueti, Leandro Ceotto Freitas-Lima, Ronaldo Carvalho Araujo, Azize Yildirim and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Claudia Stela MedeirosPrograma de Pós-Graduação em Saúde e Desenvolvimento na Região Centro-Oeste, Faculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande 79070-900, Brazil.ORCID 0000-0001-9375-1804
Ivo Vieira de Sousa NetoLaboratório de Análises Moleculares, Programa de Pós-Graduação em Ciências e Tecnologias em Saúde, Universidade de Brasília, Distrito Federal 72220-275, Brazil.ORCID 0000-0002-1479-5866
Keemilyn Karla Santos SilvaResearch in Exercise and Nutrition in Health and Sports Performance-PENSARE, Graduate Program in Movement Sciences, Universidade Federal de Mato Grosso do Sul, Campo Grande 79070-900, Brazil.
Ana Paula Castro CantuáriaCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Distrito Federal 70790-160, Brazil.ORCID 0000-0001-5828-450X
Taia Maria Berto RezendeCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Distrito Federal 70790-160, Brazil.ORCID 0000-0002-4148-0659
Octávio Luiz FrancoCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Distrito Federal 70790-160, Brazil.ORCID 0000-0001-9546-0525
Rita de Cassia MarquetiLaboratório de Análises Moleculares, Programa de Pós-Graduação em Ciências e Tecnologias em Saúde, Universidade de Brasília, Distrito Federal 72220-275, Brazil.
Leandro Ceotto Freitas-LimaDepartamento de Biofísica, Universidade Federal de São Paulo, São Paulo 04039-032, Brazil.ORCID 0000-0001-9550-6095
Ronaldo Carvalho AraujoDepartamento de Biofísica, Universidade Federal de São Paulo, São Paulo 04039-032, Brazil.ORCID 0000-0003-0095-4608
Azize YildirimDepartment of Life Science, Whitelands College, University of Roehampton, London SW15 4DJ, UK.
Richard MackenzieDepartment of Life Science, Whitelands College, University of Roehampton, London SW15 4DJ, UK.ORCID 0000-0001-6799-6218
Jeeser Alves AlmeidaPrograma de Pós-Graduação em Saúde e Desenvolvimento na Região Centro-Oeste, Faculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande 79070-900, Brazil.ORCID 0000-0002-3409-8005
Universidade de Brasília · BRUniversidade Federal de Mato Grosso do Sul · BRUniversidade Federal de São Paulo · BRUniversity of Roehampton · GBUniversidade Católica de Brasília · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 408534/2016-8Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

High-protein diets (HPDs) are widely accepted as a way to stimulate muscle protein synthesis when combined with resistance training (RT). However, the effects of HPDs on adipose tissue plasticity and local inflammation are yet to be determined. This study investigated the impact of HPDs on glucose control, adipocyte size, and epididymal adipose inflammatory biomarkers in resistance-trained rats. Eighteen Wistar rats were randomly assigned to four groups: normal-protein (NPD; 17% protein total dietary intake) and HPD (26.1% protein) without RT and NPD and HPD with RT. Trained groups received RT for 12 weeks with weights secured to their tails. Glucose and insulin tolerance tests, adipocyte size, and an array of cytokines were determined. While HPD without RT induced glucose intolerance, enlarged adipocytes, and increased TNF-α, MCP-1, and IL1-β levels in epididymal adipose tissue (

Indexed as

Diet, High-ProteinResistance TrainingAdipocytesAnimalsBlood GlucoseCell SizeDietEpididymisGlutathioneInflammationInsulin ResistanceIntra-Abdominal FatMaleOrgan SizeRatsRats, WistarBlood GlucoseGlutathioneadipokinesdietary managementexercise trainingmetabolism

Identifiers

PMID34201185
PMCPMC8227719
OpenAlexW3167788535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.