Evidence map›Paper›PMID 34201150›Full record

ArticleGenes2021

Arabidopsis NPF4.6 and NPF5.1 Control Leaf Stomatal Aperture by Regulating Abscisic Acid Transport.

Takafumi Shimizu, Yuri Kanno, Hiromi Suzuki, Shunsuke Watanabe, Mitsunori Seo

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Transcriptional gene network involved in drought stress response: application for crop breeding in the context of climate change.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  3. Review
  4. Molecular mapping of the broad bean wilt virus 2 resistance locus bwvr in Capsicum annuum using BSR-seq.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024
    Article
  5. NO and HInternational journal of molecular sciences · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Takafumi ShimizuRIKEN Center for Sustainable Resource Science, Kanagawa 230-0045, Japan.ORCID 0000-0003-4372-1337
Yuri KannoRIKEN Center for Sustainable Resource Science, Kanagawa 230-0045, Japan.
Hiromi SuzukiRIKEN Center for Sustainable Resource Science, Kanagawa 230-0045, Japan.ORCID 0000-0002-3362-9361
Shunsuke WatanabeRIKEN Center for Sustainable Resource Science, Kanagawa 230-0045, Japan.ORCID 0000-0001-6206-1923
Mitsunori SeoRIKEN Center for Sustainable Resource Science, Kanagawa 230-0045, Japan.ORCID 0000-0001-8325-7984
RIKEN Center for Sustainable Resource Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The plant hormone abscisic acid (ABA) is actively synthesized in vascular tissues and transported to guard cells to promote stomatal closure. Although several transmembrane ABA transporters have been identified, how the movement of ABA within plants is regulated is not fully understood. In this study, we determined that Arabidopsis NPF4.6, previously identified as an ABA transporter expressed in vascular tissues, is also present in guard cells and positively regulates stomatal closure in leaves. We also found that mutants defective in NPF5.1 had a higher leaf surface temperature compared to the wild type. Additionally, NPF5.1 mediated cellular ABA uptake when expressed in a heterologous yeast system. Promoter activities of

Indexed as

Abscisic AcidArabidopsisArabidopsis ProteinsMembrane Transport ProteinsPlant StomataAbscisic AcidArabidopsis ProteinsMembrane Transport Proteinsabscisic acid (ABA)Arabidopsis thaliana L.guard cellsNITRATE TRANSPORTER 1/PEPTIDE TRANSPORTER FAMILY (NPF)transporter

Identifiers

PMID34201150
PMCPMC8227765
OpenAlexW3171889667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.