Evidence map›Paper›PMID 34201111›Full record

ArticleMolecules (Basel, Switzerland)2021

In Vitro Evaluation of the Squaramide-Conjugated Fibroblast Activation Protein Inhibitor-Based Agents AAZTA

Euy Sung Moon, Yentl Van Rymenant, Sandeep Battan, Joni De Loose, An Bracke, Pieter Van der Veken, Ingrid De Meester, Frank Rösch

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Preclinical evaluation of DOTAGA.Glu.(FAPI)European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Review
  6. Preclinical evaluation of [EJNMMI radiopharmacy and chemistry · 2025
    Article
  7. Article
  8. Article
  9. Translational assessment of a DATA-functionalized FAP inhibitor with facileEuropean journal of nuclear medicine and molecular imaging · 2023
    Article
  10. Article
  11. Head-to-Head Comparison between [Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Dimeric FAPI with potential for tumor theranostics.American journal of nuclear medicine and molecular imaging · 2021
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Euy Sung MoonDepartment of Chemistry-TRIGA, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.ORCID 0000-0003-0447-1355
Yentl Van RymenantLaboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.ORCID 0000-0002-2443-5864
Sandeep BattanDepartment of Chemistry-TRIGA, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.
Joni De LooseLaboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
An BrackeLaboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
Pieter Van der VekenLaboratory of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
Ingrid De MeesterLaboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.ORCID 0000-0002-3421-0124
Frank RöschDepartment of Chemistry-TRIGA, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.
University of Antwerp · BEJohannes Gutenberg University Mainz · DE

Funding

Agentschap Innoveren en Ondernemen VLAIO HCB 2019. 2446Wetenschappelijk Onderzoek Vlaanderen (FWO) 1S64220N
6 · The paper itself

Abstract

Recently, the first squaramide-(SA) containing FAP inhibitor-derived radiotracers were introduced. DATA

Indexed as

AcetatesAzepinesEndopeptidasesFibroblast Activation Protein AlphaFibroblastsGallium RadioisotopesHeterocyclic Compounds, 1-RingHumansLigandsLutetiumMembrane ProteinsPositron Emission Tomography Computed TomographyQuinineRadioisotopesRadiopharmaceuticalsScandium1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid1,4-bis(hydroxycarbonylmethyl)-6-(bis(hydroxycarbonylmethyl))amino-6-methylperhydro-1,4-diazepineAcetatesAzepinesEndopeptidasesFibroblast Activation Protein AlphaGallium-68Gallium RadioisotopesHeterocyclic Compounds, 1-RingLigandsLutetiumLutetium-177Membrane ProteinsQuinineRadioisotopesRadiopharmaceuticalsScandiumScandium-44Serine EndopeptidasessquaramideAAZTADPPFAPlutetium-177PREPSAscandium-44

Identifiers

PMID34201111
PMCPMC8226449
OpenAlexW3166595579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.