Evidence map›Paper›PMID 34201101›Full record

ReviewCells2021

The AMPK/p27

Lauren K McKay, James P White

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  19. Review
  20. p27, The Cell Cycle and Alzheimer´s Disease.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lauren K McKayAdams School of Dentistry, UNC Chapel Hill, Chapel Hill, NC 27599, USA.
James P WhiteDuke Molecular Physiology Institute, Duke University School of Medicine, 300 N. Duke Street, Durham, NC 27701, USA.
Duke University · US

Funding

The AMPK/ULK1/p27Kip1 axis regulates autophagy and cell survival in aged satellite cellsK01AG056664 · NIA · DUKE UNIVERSITY · PI WHITE, JAMES P. · 2017 to 2022
$913k
NIA NIH HHS K01 AG056664
6 · The paper itself

Abstract

Once believed to solely function as a cyclin-dependent kinase inhibitor, p27

Indexed as

ApoptosisAutophagyAgingAnimalsCellular SenescenceCyclin-Dependent Kinase Inhibitor p27HumansSignal TransductionCDKN1B protein, humanCyclin-Dependent Kinase Inhibitor p27agingAktAMPKapoptosisautophagyp27senescence

Identifiers

PMID34201101
PMCPMC8229180
OpenAlexW3171028961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.