Evidence map›Paper›PMID 34201077›Full record

ArticleAnimals : an open access journal from MDPI2021

What Goes Wrong during Early Development of Artificially Reproduced European Eel

Pauline Jéhannet, Arjan P Palstra, Leon T N Heinsbroek, Leo Kruijt, Ron P Dirks, William Swinkels, Hans Komen

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pauline JéhannetAnimal Breeding and Genomics, Wageningen University & Research, 6708 PB Wageningen, The Netherlands.
Arjan P PalstraAnimal Breeding and Genomics, Wageningen University & Research, 6708 PB Wageningen, The Netherlands.
Leon T N HeinsbroekWageningen Eel Reproduction Experts B.V., 3708 AB Wageningen, The Netherlands.
Leo KruijtAnimal Breeding and Genomics, Wageningen University & Research, 6708 PB Wageningen, The Netherlands.
Ron P DirksFuture Genomics Technologies B.V., 2333 BE Leiden, The Netherlands.
William SwinkelsDUPAN Foundation, 6708 WH Wageningen, The Netherlands.
Hans KomenAnimal Breeding and Genomics, Wageningen University & Research, 6708 PB Wageningen, The Netherlands.
Wageningen University & Research · NL

Funding

European Maritime and Fisheries Fund 18971000009Ministerie van Economische Zaken 18971000009
6 · The paper itself

Abstract

In eels, large variations in larval mortality exist, which would impede the viable production of juvenile glass eels in captivity. The transcriptome of European eel larvae was investigated to identify physiological pathways and genes that show differential regulation between non-viable vs. viable larvae. Expression of genes involved in inflammation and host protection was higher, suggesting that non-viable larvae suffered from microbial infection. Expression of genes involved in osmoregulation was also higher, implying that non-viable larvae tried to maintain homeostasis by strong osmoregulatory adaptation. Expression of genes involved in myogenesis, neural, and sensory development was reduced in the non-viable larvae. Expression of the major histocompatibility complex class-I (

Indexed as

aquacultureEuropean eel Anguilla anguillaimmune systemmorphogenesisosmoregulationRNA-Seq

Identifiers

PMID34201077
PMCPMC8227761
OpenAlexW3170291038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.