Evidence map›Paper›PMID 34201066›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Deep Learning-Based Differentiation between Mucinous Cystic Neoplasm and Serous Cystic Neoplasm in the Pancreas Using Endoscopic Ultrasonography.

Leang Sim Nguon, Kangwon Seo, Jung-Hyun Lim, Tae-Jun Song, Sung-Hyun Cho, Jin-Seok Park, Suhyun Park

Registry-linked trialAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07543263 (An Artificial Intelligence System for Multimodal, Multi-class Diagnosis of Pancreatic Cystic Lesions Based on Endoscopic Ultrasonography), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07543263 recruitingnot on this mapstarted 2026, after this paper: background citation

An Artificial Intelligence System for Multimodal, Multi-class Diagnosis of Pancreatic Cystic Lesions Based on Endoscopic Ultrasonography

TypeobservationalSponsorQilu Hospital of Shandong UniversityRan2026 to 2028Enrolled176ConditionsPancreatic Cystic Lesion (PCL)ArmsiEUS-PCL(intelligent endoscopic ultrasound system- pancreatic cystic lesion)
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leang Sim NguonSchool of Electrical and Electronics Engineering, Chung-Ang University, Seoul 06974, Korea.
Kangwon SeoSchool of Electrical and Electronics Engineering, Chung-Ang University, Seoul 06974, Korea.
Jung-Hyun LimDivision of Gastroenterology, Department of Internal Medicine, Inha University School of Medicine, Incheon 22332, Korea.
Tae-Jun SongDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Sung-Hyun ChoDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Jin-Seok ParkDivision of Gastroenterology, Department of Internal Medicine, Inha University School of Medicine, Incheon 22332, Korea.
Suhyun ParkDepartment of Electronic and Electrical Engineering, Ewha Womans University, Seoul 03760, Korea.

Funding

Korea Medical Device Development Fund 202016B01
6 · The paper itself

Abstract

Mucinous cystic neoplasms (MCN) and serous cystic neoplasms (SCN) account for a large portion of solitary pancreatic cystic neoplasms (PCN). In this study we implemented a convolutional neural network (CNN) model using ResNet50 to differentiate between MCN and SCN. The training data were collected retrospectively from 59 MCN and 49 SCN patients from two different hospitals. Data augmentation was used to enhance the size and quality of training datasets. Fine-tuning training approaches were utilized by adopting the pre-trained model from transfer learning while training selected layers. Testing of the network was conducted by varying the endoscopic ultrasonography (EUS) image sizes and positions to evaluate the network performance for differentiation. The proposed network model achieved up to 82.75% accuracy and a 0.88 (95% CI: 0.817-0.930) area under curve (AUC) score. The performance of the implemented deep learning networks in decision-making using only EUS images is comparable to that of traditional manual decision-making using EUS images along with supporting clinical information. Gradient-weighted class activation mapping (Grad-CAM) confirmed that the network model learned the features from the cyst region accurately. This study proves the feasibility of diagnosing MCN and SCN using a deep learning network model. Further improvement using more datasets is needed.

Indexed as

convolutional neural networkdeep learningdiagnostic imagingendoscopic ultrasonographymucinous cystic neoplasmpancreatic cystic neoplasmsserous cystic neoplasm

Identifiers

PMID34201066
PMCPMC8229855

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.