Evidence map›Paper›PMID 34201056›Full record

ArticleMolecules (Basel, Switzerland)2021

In Vitro Bioaccessibility of Bioactive Compounds from Citrus Pomaces and Orange Pomace Biscuits.

Adriana Maite Fernández-Fernández, Eduardo Dellacassa, Tiziana Nardin, Roberto Larcher, Adriana Gámbaro, Alejandra Medrano-Fernandez, María Dolores Del Castillo

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Adriana Maite Fernández-FernándezDepartamento de Ciencia y Tecnología de Alimentos, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay.ORCID 0000-0003-4910-2318
Eduardo DellacassaDepartamento de Química Orgánica, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay.ORCID 0000-0002-4764-4212
Tiziana NardinDipartimento Alimenti e Trasformazione, Centro Trasferimento Tecnologico, Fondazione Edmund Mach di San Michele all'Adige, Via E. Mach, 1 38010 Trento, Italy.ORCID 0000-0001-7177-1062
Roberto LarcherDipartimento Alimenti e Trasformazione, Centro Trasferimento Tecnologico, Fondazione Edmund Mach di San Michele all'Adige, Via E. Mach, 1 38010 Trento, Italy.ORCID 0000-0002-4784-8389
Adriana GámbaroDepartamento de Ciencia y Tecnología de Alimentos, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay.
Alejandra Medrano-FernandezDepartamento de Ciencia y Tecnología de Alimentos, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay.ORCID 0000-0002-5926-6239
María Dolores Del CastilloInstituto de Investigación en Ciencias de la Alimentación (CIAL) (CSIC-UAM), C/Nicolás Cabrera, 9, Campus de la Universidad Autónoma de Madrid, 28049 Madrid, Spain.ORCID 0000-0001-6309-5383
Universidad de la República de Uruguay · UYFondazione Edmund Mach · ITInstituto de Investigación en Ciencias de la Alimentación · ES

Funding

Agencia Nacional de Investigación e Innovación POS_NAC_2016_1_130292Consejo Superior de Investigaciones Científicas 201970E117Consejo Superior de Investigaciones Científicas MHE-200003Ministerio de Ciencia e Innovación PID2019-111510RB-I00
6 · The paper itself

Abstract

The present investigation aimed to provide novel information on the chemical composition and in vitro bioaccessibility of bioactive compounds from raw citrus pomaces (mandarin varieties Clemenule and Ortanique and orange varieties Navel and Valencia). The effects of the baking process on their bioaccessibility was also assessed. Samples of pomaces and biscuits containing them as an ingredient were digested, mimicking the human enzymatic oral gastrointestinal digestion process, and the composition of the digests were analyzed. UHPLC-MS/MS results of the citrus pomaces flavonoid composition showed nobiletin, hesperidin/neohesperidin, tangeretin, heptamethoxyflavone, tetramethylscutellarein, and naringin/narirutin. The analysis of the digests indicated the bioaccessibility of compounds possessing antioxidant [6.6-11.0 mg GAE/g digest, 65.5-97.1 µmol Trolox Equivalents (TE)/g digest, and 135.5-214.8 µmol TE/g digest for total phenol content (TPC), ABTS, and ORAC-FL methods, respectively; significant reduction (

Indexed as

AnimalsAnti-Inflammatory AgentsAntioxidantsCell LineChromatography, High Pressure LiquidCitrusCitrus sinensisDigestionFlavonoidsFruitGastrointestinal TractHumansMiceOxidative StressPlant ExtractsRAW 264.7 CellsAnti-Inflammatory AgentsAntioxidantsFlavonoidsPlant Extractsanti-inflammatoryantioxidantbioaccessibilitycitrus pomacesdiabetesfunctional biscuitssensory analysisα-amylaseα-glucosidase

Identifiers

PMID34201056
PMCPMC8229244
OpenAlexW3171707030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.