Evidence map›Paper›PMID 34201050›Full record

ArticleBiomedicines2021

Prognostic Relevance of CD4

Paloma Lequerica-Fernández, Julián Suárez-Canto, Tania Rodriguez-Santamarta, Juan Pablo Rodrigo, Faustino Julián Suárez-Sánchez, Verónica Blanco-Lorenzo, Francisco Domínguez-Iglesias, Juana María García-Pedrero, Juan Carlos de Vicente

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. The Journal of international medical research · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. New insights on anti-tumor immunity of CD8Journal of translational medicine · 2025
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Type I conventional dendritic cells and CD8Frontiers in immunology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Paloma Lequerica-FernándezDepartment of Biochemistry, Hospital Universitario Central de Asturias (HUCA), C/Carretera de Rubín, s/n, 33011 Oviedo, Spain.
Julián Suárez-CantoDepartment of Pathology, Hospital Universitario de Cabueñes, 33394 Gijón, Spain.
Tania Rodriguez-SantamartaInstituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, C/Carretera de Rubín, s/n, 33011 Oviedo, Spain.ORCID 0000-0002-3721-119X
Juan Pablo RodrigoInstituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, C/Carretera de Rubín, s/n, 33011 Oviedo, Spain.ORCID 0000-0003-3063-0890
Faustino Julián Suárez-SánchezDepartment of Biochemistry, Hospital Universitario Central de Asturias (HUCA), C/Carretera de Rubín, s/n, 33011 Oviedo, Spain.
Verónica Blanco-LorenzoDepartment of Pathology, Hospital Universitario Central de Asturias (HUCA), C/Carretera de Rubín, s/n, 33011 Oviedo, Spain.
Francisco Domínguez-IglesiasDepartment of Biochemistry, Hospital Universitario Central de Asturias (HUCA), C/Carretera de Rubín, s/n, 33011 Oviedo, Spain.
Juana María García-PedreroInstituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, C/Carretera de Rubín, s/n, 33011 Oviedo, Spain.ORCID 0000-0002-5891-9488
Juan Carlos de VicenteInstituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, C/Carretera de Rubín, s/n, 33011 Oviedo, Spain.ORCID 0000-0002-0991-9465
Universidad de Oviedo · ESHospital Universitario Central de Asturias · ESHospital Universitario De Cabueñes · ES

Funding

Centro de Investigación Biomédica en Red de Cáncer CB16/12/00390Instituto de Investigación Sanitaria del Principado de Asturias (ISPA) IDI2018/155Instituto de Salud Carlos III PI19/00560Instituto de Salud Carlos III PI19/01255
6 · The paper itself

Abstract

This study investigates the relevance of tumor-infiltrating lymphocytes (TILs) in oral squamous cell carcinoma (OSCC). Immunohistochemical analysis of stromal/tumoral CD4

Indexed as

CD4CD8FOXP3NestinOCT4oral cancerPodoplaninTILs

Identifiers

PMID34201050
PMCPMC8227658
OpenAlexW3167422201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.