Evidence map›Paper›PMID 34201046›Full record

ArticleMedicina (Kaunas, Lithuania)2021

NELL-1 Increased the Osteogenic Differentiation and mRNA Expression of Spheroids Composed of Stem Cells.

Jong-Ho Lee, Young-Min Song, Sae-Kyung Min, Hyun-Jin Lee, Hye-Lim Lee, Min-Ji Kim, Yoon-Hee Park, Je-Uk Park, Jun-Beom Park

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. NELL-1: role and mechanisms in disease pathogenesis and development.Frontiers in cell and developmental biology · 2026
    Review
  2. Assessment of the Impacts ofMedicina (Kaunas, Lithuania) · 2022
    Article
  3. Review
  4. Article
  5. The Effects of Transforming Growth Factor-BioMed research international · 2022
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jong-Ho LeeDepartment of Oral and Maxillofacial Surgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Young-Min SongDepartment of Periodontics, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Sae-Kyung MinDepartment of Periodontics, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Hyun-Jin LeeDepartment of Periodontics, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-2093-2353
Hye-Lim LeeDepartment of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA 92697, USA.
Min-Ji KimCollege of Dentistry, Chosun University, Gwangju 61452, Korea.
Yoon-Hee ParkEbiogen, #405, Sungsu A1 Center 48 Ttukseom-ro 17-ga-gil, Seongdong-gu, Seoul 04785, Korea.
Je-Uk ParkDepartment of Oral and Maxillofacial Surgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Jun-Beom ParkDepartment of Periodontics, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-8915-1555

Funding

National Research Foundation of Korea (NRF) grant funded by the Korea government No. 2020R1A2C4001624
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

OsteogenesisStem CellsAlkaline PhosphataseCalcium-Binding ProteinsCell DifferentiationCells, CulturedHumansRNA, MessengerAlkaline PhosphataseCalcium-Binding ProteinsNELL1 protein, humanRNA, Messengerhuman NELL1 proteinmesenchymal stem cellsosteogenesis

Identifiers

PMID34201046
PMCPMC8229008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.