ArticleCancers2021
Impact of Early Mobilization on Recovery after Major Head and Neck Surgery with Free Flap Reconstruction.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Do multidisciplinary ERAS protocols improve flap reconstruction outcomes? A structured review of efficacy, implementation challenges, and specialty-driven adaptations.Frontiers in surgery · 2026Pooled it
- Enhanced Recovery After Surgery Guidelines and Hospital Length of Stay, Readmission, Complications, and Mortality: A Meta-Analysis of Randomized Clinical Trials.JAMA network open · 2024Pooled it
- Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod-Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial.JMIR mHealth and uHealth · 2026Trial
- Enhanced Recovery After Surgery Protocol in Transoral Robotic Surgery: A Case-Control Study.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026Article
- Defining benchmarks for postoperative mobilization based on the recommendations of the Enhanced Recovery After Surgery (ERAS) program for liver surgery: a prospective study.Surgical endoscopy · 2025Observational
- Comparison of the efficacy of Enhanced Recovery After Surgery (ERAS) protocol tailor-made for head and neck free flap oncosurgery with conventional perioperative care: A randomised clinical trial.Indian journal of anaesthesia · 2025Article
- Review
- Enhanced Recovery After Surgery Compliance and Outcomes for Head and Neck Reconstructive Surgery.JAMA otolaryngology-- head & neck surgery · 2025Article
- Physical and Psychological Burden of Bed Rest on Patients Following Free Flap Reconstruction of the Lower Limb: A Systematic Review and Possible Solutions.Journal of clinical medicine · 2025Review
- Pilot enhanced recovery after surgery protocol: Cranial vault remodeling for craniosynostosis.Surgical neurology international · 2025Article
- The Impact of an Early Mobility Protocol on Recovery Outcomes in Patients Undergoing Abdominal Surgeries.Cureus · 2024Article
- Postoperative delirium in oral and maxillofacial surgery: a scoping review.Head & face medicine · 2024Article
- Early Weight-Bearing After Fibula Free Flap Surgery.JAMA otolaryngology-- head & neck surgery · 2024Article
- Enhanced recovery after surgery (ERAS) protocol improves patient outcomes in free flap surgery for head and neck cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Association between duration of urinary catheterization and post-operative mobilization following elective cesarean section: A retrospective case-control study in Espoo, Finland.European journal of midwifery · 2024Article
- Enhanced recovery after surgery, current, and future considerations in head and neck cancer.Laryngoscope investigative otolaryngology · 2023Review
- Consumer Wearables for Patient Monitoring in Otolaryngology: A State of the Art Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2022Review
- Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Surgery with free flap reconstruction is a standard treatment for head and neck cancer (HNC). Because of the complexity of HNC surgery, recovery can be challenging, and complications are common. One of the foundations of enhanced recovery after surgery (ERAS) is early postoperative mobilization. The ERAS guidelines for HNC surgery with free flap reconstruction recommend mobilization within 24 h. This is based mainly on evidence from other surgical disciplines, and the extent to which mobilization within 24 h improves recovery after HNC surgery has not been explored. This retrospective analysis included 445 patients from the Calgary Head and Neck Enhanced Recovery Program. Mobilization after 24 h was associated with more complications of any type (OR = 1.73, 95% CI [confidence interval] = 1.16-2.57) and more major complications (OR = 1.76; 95% CI = 1.00-3.16). When accounting for patient and clinical factors, mobilization after 48 h was a significant predictor of major complications (OR = 2.61; 95% CI = 1.10-6.21) and prolonged length of stay (>10 days; OR = 2.85, 95% CI = 1.41-5.76). This comprehensive analysis of the impact of early mobilization on postoperative complications and length of stay in a large HNC cohort provides novel evidence supporting adherence to the ERAS early mobilization recommendations. Early mobilization should be a priority for patients undergoing HNC surgery with free flap reconstruction.
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Registered trials
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