Evidence map›Paper›PMID 34200896›Full record

ArticleInternational journal of molecular sciences2021

Sustained Release of Insulin-Like Growth Factor-1 from

Meng-Jin Lin, Mei-Chun Lu, Hwan-You Chang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Meng-Jin LinMiaoli District Agricultural Research and Extension Station, Council of Agriculture, Executive Yuan, Miaoli 363201, Taiwan.
Mei-Chun LuMiaoli District Agricultural Research and Extension Station, Council of Agriculture, Executive Yuan, Miaoli 363201, Taiwan.
Hwan-You ChangInstitute of Molecular Medicine, National Tsing Hua University, Hsinchu 300044, Taiwan.
National Tsing Hua University · TWCouncil of Agriculture · TW

Funding

Council of Agriculture 108 AS-1.2.1-MS-M2
6 · The paper itself

Abstract

The goals of this study are to develop a high purity patented silk fibroin (SF) film and test its suitability to be used as a slow-release delivery for insulin-like growth factor-1 (IGF-1). The release rate of the SF film delivering IGF-1 followed zero-order kinetics as determined via the Ritger and Peppas equation. The release rate constant was identified as 0.11, 0.23, and 0.09% h

Indexed as

Drug Delivery SystemsAnimalsBandagesBombyxDelayed-Action PreparationsDiabetes Mellitus, ExperimentalFemaleFibroblastsFibroinsInsulin-Like Growth Factor IMiceMice, Inbred BALB CMice, KnockoutReceptors, LeptinRe-EpithelializationWound HealingDelayed-Action PreparationsFibroinsInsulin-Like Growth Factor IReceptors, LeptinBombyx mori L.diabetesinsulin-like growth factor-1 (IGF-1)silk fibroinwound healing

Identifiers

PMID34200896
PMCPMC8230471
OpenAlexW3169214849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.