ReviewAntibiotics (Basel, Switzerland)2021
Systemic Antibiotic Prophylaxis to Reduce Early Implant Failure: A Systematic Review and Meta-Analysis.
Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Is routine antibiotic prophylaxis warranted in dental implant surgery to prevent early implant failure? - a systematic review.BMC oral health · 2024Pooled it
- Short implants compared to regular dental implants after bone augmentation in the atrophic posterior mandible: umbrella review and meta-analysis of success outcomes.International journal of implant dentistry · 2023Pooled it
- Trial
- The effect of preoperative clindamycin in reducing early oral implant failure: a randomised placebo-controlled clinical trial.Clinical oral investigations · 2023Trial
- Effect of antibiotic prophylaxis in dental implant surgery: A multicenter placebo-controlled double-blinded randomized clinical trial.Clinical implant dentistry and related research · 2022Trial
- Global prevalence and guideline adherence of antibiotic prescribing in dental implant surgery: A systematic review and meta-analysis.The Japanese dental science review · 2026Review
- Patterns of Surgical Prophylaxis Prescribing for Dentoalveolar Procedures in Australian Hospitals: 2016-2022.Australian dental journal · 2026Article
- The Prevalence of Early Implant Failure and Associated Risk Factors: A Retrospective Study.Journal of clinical and experimental dentistry · 2026Review
- Evaluation of the effectiveness of the model of family participatory care based on cloud follow-up in enhancing the quality of life and psychological well-being of patients with chronic difficult-to-heal traumatic tumours.Frontiers in public health · 2026Observational
- Amoxicillin and metronidazole resistance of bacteria isolated from dental implants with peri-implant diseases: a pilot cross-sectional study.Access microbiology · 2026Article
- Rational utilization of antibiotic prophylaxis in oral and maxillofacial surgery: a large scope review of recent data.BMC oral health · 2025Review
- Antibiotic prophylaxis in dental implant surgery - A qualitative study on the attitudes and routines of Swedish dentists.BMC oral health · 2025Article
- Effect of Antibiotic Prophylaxis in Dental Implant Surgery: A Randomized Controlled Clinical Trial.Dentistry journal · 2025Article
- Effect of preoperative antibiotic use on the implant success rate: a retrospective cohort study of cefixime and ornidazole in China.BMC oral health · 2025Article
- Overprescription of antibiotics in Brazilian dental clinics: an evaluation of current practices.Scientific reports · 2024Article
- Comparison of Prophylactic Effects between Localized Biomimetic Minocycline and Systematic Amoxicillin on Implants Placed Immediately in Infected Sockets.Biomimetics (Basel, Switzerland) · 2023Article
- Comparative Efficacy of Different Amoxicillin Dosing Regimens in Preventing Early Implant Failure-A Systematic Review with Network Meta-Analysis.Antibiotics (Basel, Switzerland) · 2023Review
- Application of Platelet-Rich Fibrin and Bone Morphogenetic Protein for Full-Mouth Implant-Based Oral Rehabilitation in a Case of Mandibular Osteoradionecrosis.Case reports in dentistry · 2023Article
- The Effectiveness of a Bioactive Healing Abutment as a Local Drug Delivery System to Impact Peri-Implant Mucositis: A Prospective Case Series Study.Pharmaceutics · 2022Article
- Antibiotic Resistance in Patients with Peri-Implantitis: A Systematic Scoping Review.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systemic antibiotics are routinely prescribed in implant procedures, but the lack of consensus causes large differences between clinicians regarding antibiotic prophylaxis regimens. The objectives of this systematic review are to assess the need to prescribe antibiotics to prevent early implant failure and find the most appropriate antibiotic prophylaxis regimen. The electronic search was conducted in PubMed/MEDLINE, Scielo and Cochrane Central Trials Database for randomized clinical trials of at least 3 months of follow-up. Eleven studies were included in the qualitative analysis. Antibiotics were found to statistically significantly reduce early implant failures (RR = 0.30, 95% CI: 0.19-0.47,
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.